There have been 50 recent insider transactions recorded for Lexicon Pharmaceuticals, Inc. (LXRX), including 27 buys and 20 sells. Total insider buying was valued at $27.27M and total insider selling at $440.54K.
Notable insiders with recent activity include Coiante Scott M, Crum Brian T, Defrancesco Lisa. Insider transactions can provide insights into how company leadership views the stock's valuation and future prospects.
Insider Transactions — LXRX
| Date |
Name |
Role |
Transaction |
Shares |
Avg. Price |
Value |
Shares Owned |
| 2026-02-28 |
Coiante Scott M |
SVP, Chief Financial Officer |
Tax Withholding of RSU |
54,881 |
$1.47 |
$80.68K |
105,356 |
| 2026-02-28 |
Crum Brian T |
SVP, General Counsel & Secr. |
Option Exercise (Sell) |
33,457 |
- |
- |
- |
| 2026-02-28 |
Defrancesco Lisa |
SVP, IR and Corp Comm |
Option Exercise (Sell) |
24,674 |
- |
- |
24,673 |
| 2026-02-28 |
Granowitz Craig B |
SVP, Chief Medical Officer |
Option Exercise (Sell) |
35,790 |
- |
- |
- |
| 2026-02-28 |
Mcdermott Wendy |
SVP, Human Resources |
Option Exercise (Sell) |
27,697 |
- |
- |
- |
| 2026-02-28 |
Exton Michael |
Chief Executive Officer |
Tax Withholding of RSU |
204,831 |
$1.47 |
$301.1K |
298,432 |
| 2026-02-28 |
Gopinathan Suma |
SVP, Discovery |
Option Exercise (Sell) |
14,000 |
- |
- |
- |
| 2026-02-28 |
Martens Rachel Yap |
SVP, Partnerships & Corp Strat |
Tax Withholding of RSU |
35,826 |
$1.47 |
$52.66K |
31,264 |
| 2026-02-25 |
Debbane Raymond |
Director |
Informative Buy |
2,000 |
$1.49 |
$2.98K |
1,906,186 |
| 2026-02-23 |
Debbane Raymond |
Director |
Informative Buy |
100,000 |
$1.47 |
$147K |
1,904,186 |
| 2026-02-20 |
Debbane Raymond |
Director |
Informative Buy |
100,000 |
$1.48 |
$147.79K |
1,804,186 |
| 2026-02-19 |
Debbane Raymond |
Director |
Informative Buy |
50,000 |
$1.44 |
$71.97K |
1,704,186 |
| 2026-02-18 |
Debbane Raymond |
Director |
Informative Buy |
133,688 |
$1.32 |
$176.47K |
1,654,186 |
| 2026-02-17 |
Debbane Raymond |
Director |
Informative Buy |
76,857 |
$1.31 |
$100.54K |
1,520,498 |
| 2026-02-17 |
Artal Participations S.a R.l. |
10 Percent Owner |
RSU Award |
41,290 |
$65.00 |
$2.68M |
408,435 |
| 2026-02-13 |
Debbane Raymond |
Director |
Informative Buy |
57,952 |
$1.31 |
$75.88K |
1,443,641 |
| 2026-02-12 |
Coiante Scott M |
SVP, Chief Financial Officer |
RSU Award |
272,680 |
- |
- |
272,680 |
| 2026-02-12 |
Crum Brian T |
SVP, General Counsel & Secr. |
RSU Award |
299,710 |
- |
- |
299,710 |
| 2026-02-12 |
Defrancesco Lisa |
SVP, IR and Corp Comm |
RSU Award |
257,530 |
- |
- |
257,530 |
| 2026-02-12 |
Granowitz Craig B |
SVP, Chief Medical Officer |
RSU Award |
346,610 |
- |
- |
346,610 |
| 2026-02-12 |
Mcdermott Wendy |
SVP, Human Resources |
RSU Award |
250,200 |
- |
- |
250,200 |
| 2026-02-12 |
Exton Michael |
Chief Executive Officer |
RSU Award |
862,440 |
- |
- |
862,440 |
| 2026-02-12 |
Gopinathan Suma |
SVP, Discovery |
RSU Award |
238,450 |
- |
- |
238,450 |
| 2026-02-12 |
Martens Rachel Yap |
SVP, Partnerships & Corp Strat |
RSU Award |
193,740 |
- |
- |
193,740 |
| 2026-02-02 |
Invus Global Management, Llc |
10 Percent Owner |
RSU Award |
367,145 |
$65.00 |
$23.86M |
367,145 |
| 2026-02-02 |
Avicenna Life Sci Master Fund Lp |
10 Percent Owner |
Unknown |
- |
- |
- |
1,538,462 |
| 2025-06-03 |
Debbane Raymond |
Director |
RSU Award |
89,312 |
- |
- |
89,312 |
| 2025-06-03 |
Sobecki Christopher J |
Director |
RSU Award |
89,312 |
- |
- |
89,312 |
| 2025-06-03 |
Barker Sam L |
Director |
RSU Award |
89,312 |
- |
- |
89,312 |
| 2025-06-03 |
Amouyal Philippe |
Director |
RSU Award |
89,312 |
- |
- |
89,312 |
| 2025-06-03 |
Swain Judith L |
Director |
RSU Award |
89,312 |
- |
- |
89,312 |
| 2025-06-03 |
Sullivan Diane E. |
Director |
RSU Award |
89,312 |
- |
- |
89,312 |
| 2025-06-03 |
Cheung Ivan |
Director |
RSU Award |
89,312 |
- |
- |
89,312 |
| 2025-06-01 |
Martens Rachel Yap |
VP, Partnerships & Corp Strat |
Unknown |
150,806 |
$1.69 |
$254.86K |
- |
| 2025-06-01 |
Gopinathan Suma |
SVP, Discovery |
Unknown |
3,790 |
$9.07 |
$34.38K |
- |
| 2025-05-13 |
Debbane Raymond |
Director |
Option Exercise (Sell) |
36,810 |
- |
- |
- |
| 2025-05-13 |
Sobecki Christopher J |
Director |
Option Exercise (Sell) |
36,810 |
- |
- |
- |
| 2025-05-13 |
Barker Sam L |
Director |
Option Exercise (Sell) |
36,810 |
- |
- |
- |
| 2025-05-13 |
Amouyal Philippe |
Director |
Option Exercise (Sell) |
36,810 |
- |
- |
- |
| 2025-05-13 |
Swain Judith L |
Director |
Option Exercise (Sell) |
36,810 |
- |
- |
- |
| 2025-05-13 |
Sullivan Diane E. |
Director |
Option Exercise (Sell) |
36,810 |
- |
- |
- |
| 2025-02-28 |
Main Alan J |
EVP, Innov & Chem Sciences |
Option Exercise (Sell) |
25,667 |
- |
- |
- |
| 2025-02-28 |
Crum Brian T |
SVP, General Counsel & Secr. |
Option Exercise (Sell) |
26,097 |
- |
- |
- |
| 2025-02-28 |
Defrancesco Lisa |
SVP, IR and Corp Comm |
Tax Withholding of RSU |
9,096 |
$0.67 |
$6.09K |
15,577 |
| 2025-02-28 |
Granowitz Craig B |
SVP, Chief Medical Officer |
Option Exercise (Sell) |
27,917 |
- |
- |
- |
| 2025-02-28 |
Alexander Kristen |
VP, Finance and Accounting |
Option Exercise (Sell) |
10,617 |
- |
- |
- |
| 2025-02-28 |
Mcdermott Wendy |
SVP, Human Resources |
Option Exercise (Sell) |
18,943 |
- |
- |
- |
| 2025-02-13 |
Main Alan J |
EVP, Innov & Chem Sciences |
RSU Award |
502,060 |
- |
- |
502,060 |
| 2025-02-13 |
Coiante Scott M |
SVP, Chief Financial Officer |
RSU Award |
480,710 |
- |
- |
480,710 |
| 2025-02-13 |
Crum Brian T |
SVP, General Counsel & Secr. |
RSU Award |
510,490 |
- |
- |
510,490 |
■ Informative Buy/Sell — open market transaction (most significant)
■ Uninformative Buy — award, option exercise, conversion
■ Uninformative Sell — tax withholding, award vest sale
■ Neutral — gift, trust, expiry