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Lexicon Pharmaceuticals, Inc. LXRX NASDAQ

NASDAQ Global Select • Healthcare • Biotechnology • US • USD

SharesGrow Score
47/100
1/7 Pass
SharesGrow Intrinsic Value
N/A
Negative cash flow
Analyst Price Target
$6.00
+222.6%

There have been 50 recent insider transactions recorded for Lexicon Pharmaceuticals, Inc. (LXRX), including 27 buys and 20 sells. Total insider buying was valued at $27.27M and total insider selling at $440.54K.

Notable insiders with recent activity include Coiante Scott M, Crum Brian T, Defrancesco Lisa. Insider transactions can provide insights into how company leadership views the stock's valuation and future prospects.

Insider Transactions — LXRX

Date Name Role Transaction Shares Avg. Price Value Shares Owned
2026-02-28 Coiante Scott M SVP, Chief Financial Officer Tax Withholding of RSU 54,881 $1.47 $80.68K 105,356
2026-02-28 Crum Brian T SVP, General Counsel & Secr. Option Exercise (Sell) 33,457 - - -
2026-02-28 Defrancesco Lisa SVP, IR and Corp Comm Option Exercise (Sell) 24,674 - - 24,673
2026-02-28 Granowitz Craig B SVP, Chief Medical Officer Option Exercise (Sell) 35,790 - - -
2026-02-28 Mcdermott Wendy SVP, Human Resources Option Exercise (Sell) 27,697 - - -
2026-02-28 Exton Michael Chief Executive Officer Tax Withholding of RSU 204,831 $1.47 $301.1K 298,432
2026-02-28 Gopinathan Suma SVP, Discovery Option Exercise (Sell) 14,000 - - -
2026-02-28 Martens Rachel Yap SVP, Partnerships & Corp Strat Tax Withholding of RSU 35,826 $1.47 $52.66K 31,264
2026-02-25 Debbane Raymond Director Informative Buy 2,000 $1.49 $2.98K 1,906,186
2026-02-23 Debbane Raymond Director Informative Buy 100,000 $1.47 $147K 1,904,186
2026-02-20 Debbane Raymond Director Informative Buy 100,000 $1.48 $147.79K 1,804,186
2026-02-19 Debbane Raymond Director Informative Buy 50,000 $1.44 $71.97K 1,704,186
2026-02-18 Debbane Raymond Director Informative Buy 133,688 $1.32 $176.47K 1,654,186
2026-02-17 Debbane Raymond Director Informative Buy 76,857 $1.31 $100.54K 1,520,498
2026-02-17 Artal Participations S.a R.l. 10 Percent Owner RSU Award 41,290 $65.00 $2.68M 408,435
2026-02-13 Debbane Raymond Director Informative Buy 57,952 $1.31 $75.88K 1,443,641
2026-02-12 Coiante Scott M SVP, Chief Financial Officer RSU Award 272,680 - - 272,680
2026-02-12 Crum Brian T SVP, General Counsel & Secr. RSU Award 299,710 - - 299,710
2026-02-12 Defrancesco Lisa SVP, IR and Corp Comm RSU Award 257,530 - - 257,530
2026-02-12 Granowitz Craig B SVP, Chief Medical Officer RSU Award 346,610 - - 346,610
2026-02-12 Mcdermott Wendy SVP, Human Resources RSU Award 250,200 - - 250,200
2026-02-12 Exton Michael Chief Executive Officer RSU Award 862,440 - - 862,440
2026-02-12 Gopinathan Suma SVP, Discovery RSU Award 238,450 - - 238,450
2026-02-12 Martens Rachel Yap SVP, Partnerships & Corp Strat RSU Award 193,740 - - 193,740
2026-02-02 Invus Global Management, Llc 10 Percent Owner RSU Award 367,145 $65.00 $23.86M 367,145
2026-02-02 Avicenna Life Sci Master Fund Lp 10 Percent Owner Unknown - - - 1,538,462
2025-06-03 Debbane Raymond Director RSU Award 89,312 - - 89,312
2025-06-03 Sobecki Christopher J Director RSU Award 89,312 - - 89,312
2025-06-03 Barker Sam L Director RSU Award 89,312 - - 89,312
2025-06-03 Amouyal Philippe Director RSU Award 89,312 - - 89,312
2025-06-03 Swain Judith L Director RSU Award 89,312 - - 89,312
2025-06-03 Sullivan Diane E. Director RSU Award 89,312 - - 89,312
2025-06-03 Cheung Ivan Director RSU Award 89,312 - - 89,312
2025-06-01 Martens Rachel Yap VP, Partnerships & Corp Strat Unknown 150,806 $1.69 $254.86K -
2025-06-01 Gopinathan Suma SVP, Discovery Unknown 3,790 $9.07 $34.38K -
2025-05-13 Debbane Raymond Director Option Exercise (Sell) 36,810 - - -
2025-05-13 Sobecki Christopher J Director Option Exercise (Sell) 36,810 - - -
2025-05-13 Barker Sam L Director Option Exercise (Sell) 36,810 - - -
2025-05-13 Amouyal Philippe Director Option Exercise (Sell) 36,810 - - -
2025-05-13 Swain Judith L Director Option Exercise (Sell) 36,810 - - -
2025-05-13 Sullivan Diane E. Director Option Exercise (Sell) 36,810 - - -
2025-02-28 Main Alan J EVP, Innov & Chem Sciences Option Exercise (Sell) 25,667 - - -
2025-02-28 Crum Brian T SVP, General Counsel & Secr. Option Exercise (Sell) 26,097 - - -
2025-02-28 Defrancesco Lisa SVP, IR and Corp Comm Tax Withholding of RSU 9,096 $0.67 $6.09K 15,577
2025-02-28 Granowitz Craig B SVP, Chief Medical Officer Option Exercise (Sell) 27,917 - - -
2025-02-28 Alexander Kristen VP, Finance and Accounting Option Exercise (Sell) 10,617 - - -
2025-02-28 Mcdermott Wendy SVP, Human Resources Option Exercise (Sell) 18,943 - - -
2025-02-13 Main Alan J EVP, Innov & Chem Sciences RSU Award 502,060 - - 502,060
2025-02-13 Coiante Scott M SVP, Chief Financial Officer RSU Award 480,710 - - 480,710
2025-02-13 Crum Brian T SVP, General Counsel & Secr. RSU Award 510,490 - - 510,490
Informative Buy/Sell — open market transaction (most significant) Uninformative Buy — award, option exercise, conversion Uninformative Sell — tax withholding, award vest sale Neutral — gift, trust, expiry
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