There have been 50 recent insider transactions recorded for Prime Medicine, Inc. (PRME), including 39 buys and 10 sells. Total insider buying was valued at $55.47M and total insider selling at $11.7M.
Notable insiders with recent activity include Reine Allan, Alenson Carman, Lee Ann L.. Insider transactions can provide insights into how company leadership views the stock's valuation and future prospects.
Insider Transactions — PRME
| Date |
Name |
Role |
Transaction |
Shares |
Avg. Price |
Value |
Shares Owned |
| 2026-02-26 |
Reine Allan |
Chief Executive Officer |
RSU Award |
1,300,000 |
$4.38 |
$5.69M |
1,300,000 |
| 2026-02-23 |
Alenson Carman |
See Remarks |
RSU Award |
140,000 |
$3.34 |
$467.6K |
140,000 |
| 2026-02-23 |
Lee Ann L. |
Chief Technical Officer |
RSU Award |
375,000 |
$3.34 |
$1.25M |
375,000 |
| 2025-08-01 |
Nelsen Robert |
10 Percent Owner |
Informative Buy |
3,030,300 |
$3.30 |
$10M |
6,230,300 |
| 2025-08-01 |
Arch Venture Partners X, Llc |
10 Percent Owner |
Informative Buy |
3,030,300 |
$3.30 |
$10M |
6,230,300 |
| 2025-08-01 |
Arch Venture Partners Xii, Llc |
10 Percent Owner |
Informative Buy |
3,030,300 |
$3.30 |
$10M |
6,230,300 |
| 2025-08-01 |
Nelsen Robert |
10 Percent Owner |
Return of Shares |
39,062 |
$14.83 |
$579.29K |
- |
| 2025-08-01 |
Foster-cheek Kaye I |
Director |
Return of Shares |
13,510 |
$10.92 |
$147.53K |
- |
| 2025-08-01 |
Schenkein David P |
Director |
Return of Shares |
39,062 |
$14.83 |
$579.29K |
- |
| 2025-08-01 |
Marrazzo Jeffrey D |
Director |
Return of Shares |
250,000 |
$8.63 |
$2.16M |
- |
| 2025-08-01 |
Alenson Carman |
See Remarks |
Return of Shares |
6,254 |
$13.63 |
$85.24K |
- |
| 2025-08-01 |
Reine Allan |
Chief Executive Officer |
Return of Shares |
850,000 |
$6.80 |
$5.78M |
- |
| 2025-08-01 |
Lee Ann L. |
Chief Technical Officer |
Return of Shares |
180,995 |
$8.49 |
$1.54M |
- |
| 2025-08-01 |
Kelly Michael Aaron |
Director |
Return of Shares |
45,000 |
$7.68 |
$345.6K |
- |
| 2025-08-01 |
Gv 2021 Gp, L.l.c. |
10 Percent Owner |
Informative Buy |
1,500,000 |
$3.30 |
$4.95M |
3,262,440 |
| 2025-08-01 |
Chung Wendy |
Director |
Return of Shares |
13,510 |
$10.54 |
$142.4K |
- |
| 2025-08-01 |
Cahill Thomas |
Director |
Return of Shares |
45,000 |
$7.68 |
$345.6K |
- |
| 2025-06-30 |
Liu David R. |
10 Percent Owner |
Informative Buy |
21,000 |
$2.52 |
$52.83K |
20,240,945 |
| 2025-06-23 |
Liu David R. |
10 Percent Owner |
Informative Buy |
21,000 |
$2.16 |
$45.4K |
20,219,945 |
| 2025-06-16 |
Liu David R. |
10 Percent Owner |
Informative Buy |
21,000 |
$1.49 |
$31.2K |
20,198,945 |
| 2025-06-11 |
Liu David R. |
10 Percent Owner |
Informative Buy |
21,000 |
$1.60 |
$33.59K |
20,177,945 |
| 2025-06-04 |
Nelsen Robert |
10 Percent Owner |
RSU Award |
55,000 |
$1.32 |
$72.6K |
55,000 |
| 2025-06-04 |
Foster-cheek Kaye I |
Director |
RSU Award |
55,000 |
$1.32 |
$72.6K |
55,000 |
| 2025-06-04 |
Schenkein David P |
Director |
RSU Award |
55,000 |
$1.32 |
$72.6K |
55,000 |
| 2025-06-04 |
Marrazzo Jeffrey D |
Director |
RSU Award |
55,000 |
$1.32 |
$72.6K |
55,000 |
| 2025-06-04 |
Kelly Michael Aaron |
Director |
RSU Award |
55,000 |
$1.32 |
$72.6K |
55,000 |
| 2025-06-04 |
Chung Wendy |
Director |
RSU Award |
55,000 |
$1.32 |
$72.6K |
55,000 |
| 2025-06-04 |
Cahill Thomas |
Director |
RSU Award |
55,000 |
$1.32 |
$72.6K |
55,000 |
| 2025-05-21 |
Reine Allan |
Chief Executive Officer |
Informative Buy |
125,000 |
$1.18 |
$147.15K |
125,000 |
| 2025-05-21 |
Lee Ann L. |
Chief Technical Officer |
Informative Buy |
100,000 |
$1.13 |
$113K |
100,000 |
| 2025-05-20 |
Brudnick Richard |
Chief Business Officer |
Informative Buy |
20,000 |
$1.19 |
$23.79K |
20,000 |
| 2025-05-19 |
Marrazzo Jeffrey D |
Director |
RSU Award |
800,000 |
$1.34 |
$1.07M |
800,000 |
| 2025-05-19 |
Reine Allan |
Chief Executive Officer |
RSU Award |
2,000,000 |
$1.34 |
$2.67M |
2,000,000 |
| 2025-05-08 |
Gottesdiener Keith Michael |
See Remarks |
RSU Award |
100,000 |
$8.32 |
$832K |
300,000 |
| 2025-05-08 |
Reine Allan |
Chief Financial Officer |
RSU Award |
75,000 |
$6.80 |
$510K |
850,000 |
| 2025-05-08 |
Lee Ann L. |
Chief Technical Officer |
RSU Award |
80,416 |
$3.67 |
$295.13K |
241,248 |
| 2025-02-28 |
Gottesdiener Keith Michael |
See Remarks |
RSU Award |
500,000 |
$2.52 |
$1.26M |
500,000 |
| 2025-02-27 |
Alenson Carman |
See Remarks |
RSU Award |
90,500 |
$2.42 |
$219.01K |
90,500 |
| 2025-02-27 |
Brudnick Richard |
Chief Business Officer |
RSU Award |
225,000 |
$2.42 |
$544.5K |
225,000 |
| 2025-02-27 |
Reine Allan |
Chief Financial Officer |
RSU Award |
275,000 |
$2.42 |
$665.5K |
275,000 |
| 2025-02-27 |
Lee Ann L. |
Chief Technical Officer |
RSU Award |
275,000 |
$2.42 |
$665.5K |
275,000 |
| 2025-02-27 |
Duffield Jeremy |
Chief Scientific Officer |
RSU Award |
275,000 |
$2.42 |
$665.5K |
275,000 |
| 2025-02-27 |
Goldwasser Meredith |
SVP, Strategy & Corporate Ops. |
RSU Award |
90,500 |
$2.42 |
$219.01K |
90,500 |
| 2024-12-05 |
Gottesdiener Keith Michael |
See Remarks |
RSU Award |
100,000 |
$8.32 |
$832K |
200,000 |
| 2024-12-05 |
Brudnick Richard |
Chief Business Officer |
RSU Award |
19,300 |
$7.96 |
$153.63K |
57,900 |
| 2024-12-05 |
Reine Allan |
Chief Financial Officer |
RSU Award |
75,000 |
$6.80 |
$510K |
775,000 |
| 2024-10-08 |
Gottesdiener Keith Michael |
See Remarks |
Gift (Given) |
226,925 |
- |
- |
50,241 |
| 2024-06-12 |
Nelsen Robert |
10 Percent Owner |
RSU Award |
45,000 |
$7.68 |
$345.6K |
45,000 |
| 2024-06-12 |
Foster-cheek Kaye I |
Director |
RSU Award |
45,000 |
$7.68 |
$345.6K |
45,000 |
| 2024-06-12 |
Schenkein David P |
Director |
RSU Award |
45,000 |
$7.68 |
$345.6K |
45,000 |
■ Informative Buy/Sell — open market transaction (most significant)
■ Uninformative Buy — award, option exercise, conversion
■ Uninformative Sell — tax withholding, award vest sale
■ Neutral — gift, trust, expiry
