Alnylam Pharmaceuticals, Inc. (ALNY) has 20 known insider and institutional holders on record. The largest holder is MARAGANORE JOHN with 234,299 shares. Other notable holders include Greenstreet Yvonne and Poulton Jeffrey V..
Over the last 12 months, insiders have made 34 transactions in ALNY stock — 15 buys (valued at $10.26M) and 13 sells (valued at $923.72K). Insider buying has outpaced selling during this period, which may signal confidence in the company's prospects.
ALNY Insider Ownership
Top Holder
MARAGANORE JOHN
234,299 shares
Buys (12 mo)
15
$10.26M value
Sells (12 mo)
13
$923.72K value
12-Month Transaction Activity
Top Insider Holders
| # |
Name |
Role |
Shares Owned |
Last Filed |
Relative Size |
| 1 |
Maraganore John |
Chief Executive Officer |
234,299 |
2021-12-23 |
|
| 2 |
Greenstreet Yvonne |
Chief Executive Officer |
95,695 |
2026-03-06 |
|
| 3 |
Poulton Jeffrey V. |
EVP, Chief Financial Officer |
61,805 |
2026-03-06 |
|
| 4 |
Tanguler Tolga |
EVP, Chief Commercial Officer |
34,297 |
2026-03-06 |
|
| 5 |
Greene Barry E |
President |
23,816 |
2020-08-11 |
|
| 6 |
Vaishnaw Akshay |
President |
22,972 |
2023-08-07 |
|
| 7 |
Fitzgerald Kevin Joseph |
CSO & EVP, Head of Research |
21,227 |
2026-03-06 |
|
| 8 |
Garg Pushkal |
EVP Chief R&d |
21,097 |
2026-03-06 |
|
| 9 |
Mclaughlin Melissa |
Chief Human Resources Officer |
11,729 |
2026-04-07 |
|
| 10 |
Sharp Phillip A |
Director |
5,228 |
2024-05-20 |
|
| 11 |
Paul Steven M |
Director |
4,032 |
2021-07-19 |
|
| 12 |
Fanucci Marsha |
Director |
3,454 |
2023-05-19 |
|
| 13 |
Franchini Indrani Lall |
EVP, CLO & Secretary |
1,754 |
2024-02-29 |
|
| 14 |
Schulman Amy W |
Director |
1,558 |
2025-05-12 |
|
| 15 |
Bonney Michael W |
Director |
1,558 |
2025-05-12 |
|
| 16 |
Hesslein Robert W. |
EVP, CLO and Secretary |
1,529 |
2025-03-05 |
|
| 17 |
Keating Laurie |
EVP, Chief Legal Officer |
1,124 |
2021-08-09 |
|
| 18 |
Ausiello Dennis A |
Director |
911 |
2025-05-12 |
|
| 19 |
Hamburg Margaret A |
Director |
911 |
2025-05-12 |
|
| 20 |
Pyott David E I |
Director |
911 |
2025-05-12 |
|
Recent Transactions (last 12 months)
| Date |
Name |
Role |
Type |
Shares |
Price |
Value |
| 2026-04-06 |
Mclaughlin Melissa |
Chief Human Resources Officer |
Informative Sell |
199 |
$333.94 |
$66.45K |
| 2026-04-02 |
Mclaughlin Melissa |
Chief Human Resources Officer |
Informative Sell |
8 |
$325.49 |
$2.6K |
| 2026-03-25 |
Mclaughlin Melissa |
Chief Human Resources Officer |
Unknown |
3,567 |
$325.07 |
$1.16M |
| 2026-03-05 |
Fitzgerald Kevin Joseph |
CSO & EVP, Head of Research |
Informative Sell |
153 |
$326.24 |
$49.91K |
| 2026-03-04 |
Fitzgerald Kevin Joseph |
CSO & EVP, Head of Research |
Informative Sell |
57 |
$325.67 |
$18.56K |
| 2026-03-04 |
Tanguler Tolga |
EVP, Chief Commercial Officer |
Informative Sell |
208 |
$325.67 |
$67.74K |
| 2026-03-05 |
Garg Pushkal |
EVP Chief R&d |
Informative Sell |
500 |
$326.08 |
$163.04K |
| 2026-03-04 |
Garg Pushkal |
EVP Chief R&d |
Informative Sell |
208 |
$325.67 |
$67.74K |
| 2026-03-04 |
Poulton Jeffrey V. |
EVP, Chief Financial Officer |
Informative Sell |
223 |
$325.67 |
$72.62K |
| 2026-03-04 |
Greenstreet Yvonne |
Chief Executive Officer |
Informative Sell |
265 |
$325.67 |
$86.3K |
| 2026-03-03 |
Fitzgerald Kevin Joseph |
CSO & EVP, Head of Research |
Informative Sell |
359 |
$321.58 |
$115.45K |
| 2026-03-02 |
Fitzgerald Kevin Joseph |
CSO & EVP, Head of Research |
RSU Award |
8,105 |
$325.07 |
$2.63M |
| 2026-03-02 |
Tanguler Tolga |
EVP, Chief Commercial Officer |
Informative Sell |
170 |
$329.71 |
$56.05K |
| 2026-03-03 |
Garg Pushkal |
EVP Chief R&d |
Informative Sell |
463 |
$321.50 |
$148.85K |
| 2026-03-02 |
Garg Pushkal |
EVP Chief R&d |
RSU Award |
10,480 |
$325.07 |
$3.41M |
| 2026-03-02 |
Poulton Jeffrey V. |
EVP, Chief Financial Officer |
RSU Award |
10,480 |
$325.07 |
$3.41M |
| 2025-06-02 |
Greenstreet Yvonne |
Chief Executive Officer |
Option Exercise (Sell) |
12,080 |
$119.13 |
$1.44M |
| 2025-05-30 |
Greenstreet Yvonne |
Chief Executive Officer |
Option Exercise (Sell) |
19,559 |
$118.05 |
$2.31M |
| 2025-05-16 |
Greenstreet Yvonne |
Chief Executive Officer |
Gift (Given) |
8,376 |
- |
- |
| 2025-05-15 |
Bonney Michael W |
Director |
Option Exercise (Sell) |
11,250 |
$131.21 |
$1.48M |
| 2025-05-08 |
Reitan Colleen F |
Director |
RSU Award |
775 |
- |
- |
| 2025-04-16 |
Reitan Colleen F |
Director |
Informative Sell |
36 |
$232.86 |
$8.38K |
| 2024-10-17 |
Reitan Colleen F |
Director |
Informative Buy |
4 |
$302.67 |
$1.21K |
| 2024-08-29 |
Reitan Colleen F |
Director |
Informative Buy |
32 |
$286.00 |
$9.15K |
| 2025-05-08 |
Bertozzi Carolyn R |
Director |
RSU Award |
775 |
- |
- |
