Codexis, Inc. (CDXS) has 20 known insider and institutional holders on record. The largest holder is Opaleye Management Inc. with 12,248,318 shares. Other notable holders include Raizen Energia Participacoes S.A. and Shell Brazil Holding B.V..
Over the last 12 months, insiders have made 49 transactions in CDXS stock — 30 buys (valued at $9.11M) and 18 sells (valued at $964.21K). Insider buying has outpaced selling during this period, which may signal confidence in the company's prospects.
CDXS Insider Ownership
Top Holder
Opaleye Management Inc.
12,248,318 shares
Buys (12 mo)
30
$9.11M value
Sells (12 mo)
18
$964.21K value
12-Month Transaction Activity
Top Insider Holders
| # |
Name |
Role |
Shares Owned |
Last Filed |
Relative Size |
| 1 |
Opaleye Management Inc. |
10 Percent Owner |
12,248,318 |
2025-12-15 |
|
| 2 |
Raizen Energia Participacoes S.a. |
10 Percent Owner |
5,573,319 |
2011-06-03 |
|
| 3 |
Shell Brazil Holding B.v. |
10 Percent Owner |
5,573,319 |
2011-06-02 |
|
| 4 |
Equilon Enterprises Llc |
10 Percent Owner |
5,573,319 |
2011-05-24 |
|
| 5 |
Ispagnac Participacoes Ltda. |
10 Percent Owner |
5,573,319 |
2011-06-03 |
|
| 6 |
Moore Alison |
President and CEO |
993,000 |
2026-02-25 |
|
| 7 |
Dilly Stephen George |
Director |
727,053 |
2025-11-12 |
|
| 8 |
Maxygen Inc |
10 Percent Owner |
524,643 |
2010-12-17 |
|
| 9 |
Lutz Stefan |
Chief Scientific Officer |
316,100 |
2026-02-25 |
|
| 10 |
Erbez Georgia |
See Remarks |
316,100 |
2026-02-25 |
|
| 11 |
Sheehy Douglas T. |
See Remarks |
247,617 |
2016-03-08 |
|
| 12 |
Shaw Alan |
President and CEO |
225,846 |
2011-12-19 |
|
| 13 |
Dorgan Byron L |
Director |
223,581 |
2024-06-13 |
|
| 14 |
Kelley Bernard J |
Director |
206,136 |
2021-04-22 |
|
| 15 |
Nicols John J |
Director |
178,570 |
2023-04-19 |
|
| 16 |
Ryali Sriram |
Chief Financial Officer |
175,791 |
2024-01-02 |
|
| 17 |
Norrett Kevin |
Chief Operating Officer |
161,250 |
2025-02-07 |
|
| 18 |
Parker H Stewart |
Director |
143,583 |
2025-06-12 |
|
| 19 |
Wolf Dennis P |
Director |
138,951 |
2025-11-25 |
|
| 20 |
Singhvi Rahul |
Director |
137,052 |
2025-06-12 |
|
Recent Transactions (last 12 months)
| Date |
Name |
Role |
Type |
Shares |
Price |
Value |
| 2026-02-24 |
Lutz Stefan |
Chief Scientific Officer |
Informative Sell |
5,862 |
$1.13 |
$6.64K |
| 2026-02-23 |
Lutz Stefan |
Chief Scientific Officer |
RSU Award |
316,100 |
$1.07 |
$338.23K |
| 2026-02-23 |
Moore Alison |
President and CEO |
RSU Award |
993,000 |
$1.07 |
$1.06M |
| 2026-02-23 |
Erbez Georgia |
See Remarks |
RSU Award |
316,100 |
$1.07 |
$338.23K |
| 2026-02-06 |
Lutz Stefan |
Chief Scientific Officer |
Informative Sell |
2,492 |
$1.31 |
$3.26K |
| 2026-02-06 |
Moore Alison |
President and CEO |
Informative Sell |
3,826 |
$1.31 |
$5K |
| 2026-02-06 |
Erbez Georgia |
See Remarks |
Informative Sell |
3,826 |
$1.31 |
$5K |
| 2026-01-07 |
Lutz Stefan |
CSO |
Informative Sell |
4,685 |
$1.70 |
$7.95K |
| 2025-11-26 |
Opaleye Management Inc. |
10 Percent Owner |
Informative Sell |
148,318 |
$1.74 |
$258.27K |
| 2025-11-07 |
Opaleye Management Inc. |
10 Percent Owner |
Informative Sell |
296,682 |
$1.70 |
$503.41K |
| 2025-12-01 |
Opaleye Management Inc. |
10 Percent Owner |
Informative Sell |
8,533 |
$1.67 |
$14.23K |
| 2025-11-28 |
Opaleye Management Inc. |
10 Percent Owner |
Informative Sell |
2,490 |
$1.75 |
$4.36K |
| 2025-11-26 |
Opaleye Management Inc. |
10 Percent Owner |
Informative Sell |
5,000 |
$1.74 |
$8.71K |
| 2025-11-21 |
Wolf Dennis P |
Director |
Informative Sell |
8,952 |
$1.56 |
$13.99K |
| 2025-11-07 |
Lutz Stefan |
CSO |
Unknown |
8,800 |
$11.79 |
$103.75K |
| 2025-11-13 |
Moore Alison |
President and CEO |
RSU Award |
85,000 |
- |
- |
| 2025-11-12 |
Opaleye Management Inc. |
10 Percent Owner |
Informative Sell |
27,459 |
$1.94 |
$53.19K |
| 2025-11-11 |
De Vre Raymond |
Director |
Informative Sell |
1,413 |
$1.74 |
$2.46K |
| 2025-11-11 |
Opaleye Management Inc. |
10 Percent Owner |
Informative Sell |
13,211 |
$1.80 |
$23.77K |
| 2025-11-10 |
Opaleye Management Inc. |
10 Percent Owner |
Informative Sell |
3,318 |
$1.73 |
$5.76K |
| 2025-11-07 |
Opaleye Management Inc. |
10 Percent Owner |
Informative Sell |
10,000 |
$1.70 |
$16.97K |
| 2025-11-11 |
Dilly Stephen George |
Director |
RSU Award |
50,000 |
$1.85 |
$92.37K |
| 2025-10-13 |
Moore Alison |
Chief Technical Officer |
Informative Sell |
6,239 |
$2.51 |
$15.63K |
| 2025-10-13 |
Erbez Georgia |
Chief Financial Officer |
Informative Sell |
6,239 |
$2.51 |
$15.63K |
| 2025-08-04 |
Opaleye Management Inc. |
10 Percent Owner |
Informative Buy |
780 |
$2.84 |
$2.21K |
