Puma Biotechnology, Inc. PBYI NASDAQ

NASDAQ Global Select • Healthcare • Biotechnology • US • USD

Puma Biotechnology, Inc. (PBYI) has 20 known insider and institutional holders on record. The largest holder is ADAGE CAPITAL PARTNERS GP LLC with 5,686,668 shares. Other notable holders include ADAGE CAPITAL PARTNERS GP, L.L.C. and Adage Capital Partners, L.P..

Over the last 12 months, insiders have made 30 transactions in PBYI stock — 10 buys (valued at $2.43M) and 20 sells (valued at $1.05M). Insider selling has exceeded buying during this period.

PBYI Insider Ownership

Top Holder

ADAGE CAPITAL PARTNERS GP LLC

5,686,668 shares

Buys (12 mo)

$2.43M value

Sells (12 mo)

$1.05M value

12-Month Transaction Activity

Buy 33%

Sell 67%

Top Insider Holders

#	Name	Role	Shares Owned	Last Filed	Relative Size
1	Adage Capital Partners Gp Llc	10 Percent Owner	5,686,668	2013-11-12	100%
2	Adage Capital Partners Gp, L.l.c.	10 Percent Owner	3,843,840	2017-06-12	68%
3	Adage Capital Partners, L.p.	10 Percent Owner	3,200,000	2012-01-31	56%
4	Siddiqi Faraaz	10 Percent Owner, Officer: Secretary	1,000,000	2007-11-20	18%
5	Johnson Robert Andrew	10 Percent Owner, Officer: President	1,000,000	2007-11-21	18%
6	Munjal Kapil	10 Percent Owner	1,000,000	2007-11-16	18%
7	Auerbach Alan H	10 Percent Owner, Officer: President and CEO	227,474	2026-02-20	4%
8	Bryce Richard Paul	See Remarks	121,662	2021-04-06	2%
9	Stuglik Brian M	Director	94,958	2025-06-17	2%
10	Dorval Allison	Director	75,390	2025-06-17	1%
11	Hunt Douglas M	See Remarks	70,321	2026-02-20	1%
12	Nougues Maximo F	Chief Financial Officer	66,541	2026-02-20	1%
13	Ludwig Jeffrey Jerome	Chief Commercial Officer	66,221	2025-02-11	1%
14	Wong Alvin F	Chief Scientific Officer	59,946	2024-02-14	1%
15	Miller Michael Patrick	Director	54,000	2025-11-13	1%
16	Moyes Jay M	Director	53,322	2025-06-17	1%
17	Zavrl Frank	Director	50,993	2020-06-11	1%
18	Wilson Troy Edward	Director	43,550	2025-06-17	1%
19	Cesano Alessandra	Director	41,850	2025-07-22	1%
20	Miller Ann Calby	Director	40,732	2021-06-17	1%

Recent Transactions (last 12 months)

Date	Name	Role	Type	Shares	Price	Value
2026-02-18	Nougues Maximo F	Chief Financial Officer	RSU Award	66,541	$6.68	$444.49K
2026-02-18	Hunt Douglas M	See Remarks	RSU Award	70,321	$6.68	$469.74K
2026-02-18	Auerbach Alan H	10 Percent Owner, Officer: President and CEO	RSU Award	227,474	$6.68	$1.52M
2026-01-07	Nougues Maximo F	Chief Financial Officer	Informative Sell	6,405	$5.88	$37.65K
2026-01-06	Nougues Maximo F	Chief Financial Officer	Informative Sell	4,540	$5.84	$26.53K
2026-01-07	Hunt Douglas M	See Remarks	Informative Sell	5,014	$5.88	$29.48K
2026-01-06	Hunt Douglas M	See Remarks	Informative Sell	3,973	$5.84	$23.22K
2026-01-07	Auerbach Alan H	10 Percent Owner, Officer: President and CEO	Informative Sell	18,012	$5.88	$105.89K
2026-01-06	Auerbach Alan H	10 Percent Owner, Officer: President and CEO	Informative Sell	16,938	$5.84	$98.99K
2025-11-11	Miller Michael Patrick	Director	Informative Sell	20,000	$4.86	$97.23K
2025-07-18	Cesano Alessandra	Director	Informative Sell	27,000	$3.37	$90.91K
2025-07-09	Nougues Maximo F	Chief Financial Officer	Informative Sell	3,935	$3.54	$13.91K
2025-07-08	Nougues Maximo F	Chief Financial Officer	Informative Sell	5,587	$3.53	$19.74K
2025-07-09	Hunt Douglas M	See Remarks	Informative Sell	3,443	$3.54	$12.17K
2025-07-08	Hunt Douglas M	See Remarks	Informative Sell	4,374	$3.53	$15.45K
2025-07-09	Auerbach Alan H	10 Percent Owner, Officer: President and CEO	Informative Sell	21,580	$3.54	$76.29K
2025-07-08	Auerbach Alan H	10 Percent Owner, Officer: President and CEO	Informative Sell	25,592	$3.53	$90.42K
2025-06-13	Cesano Alessandra	Director	Informative Sell	12,150	$3.40	$41.31K
2025-06-13	Stuglik Brian M	Director	Informative Sell	8,100	$3.39	$27.46K
2025-06-13	Dorval Allison	Director	Informative Sell	11,610	$3.40	$39.47K
2025-06-13	Senderowicz Adrian	Director	Informative Sell	27,000	$3.40	$91.8K
2025-06-13	Wilson Troy Edward	Director	Informative Sell	10,800	$3.40	$36.72K
2025-06-13	Moyes Jay M	Director	Informative Sell	22,000	$3.40	$74.8K
2025-06-11	Cesano Alessandra	Director	RSU Award	27,000	-	-
2025-06-11	Stuglik Brian M	Director	RSU Award	27,000	-	-