Prelude Therapeutics Incorporated (PRLD) has 18 known insider and institutional holders on record. The largest holder is ORBIMED ADVISORS LLC with 10,119,756 shares. Other notable holders include Vaddi Krishna and Lim Bryant David.
Over the last 12 months, insiders have made 16 transactions in PRLD stock — 11 buys (valued at $4.06M) and 0 sells (valued at RSU Award). Insider buying has outpaced selling during this period, which may signal confidence in the company's prospects.
PRLD Insider Ownership
Top Holder
ORBIMED ADVISORS LLC
10,119,756 shares
Buys (12 mo)
11
$4.06M value
Sells (12 mo)
0
$0.00 value
12-Month Transaction Activity
Top Insider Holders
| # |
Name |
Role |
Shares Owned |
Last Filed |
Relative Size |
| 1 |
Orbimed Advisors Llc |
10 Percent Owner |
10,119,756 |
2023-05-24 |
|
| 2 |
Vaddi Krishna |
CEO |
837,000 |
2026-02-05 |
|
| 3 |
Lim Bryant David |
CLO, CFO, Corp Sec. |
275,000 |
2026-02-05 |
|
| 4 |
Scherle Peggy |
Chief Scientific Officer |
230,000 |
2026-02-05 |
|
| 5 |
Combs Andrew |
Chief Chemistry Officer |
230,000 |
2026-02-05 |
|
| 6 |
Chardonnet Laurent |
Chief Financial Officer |
150,000 |
2024-03-04 |
|
| 7 |
Sandor Victor |
Director |
121,285 |
2025-11-07 |
|
| 8 |
Piper Brian |
Chief Financial Officer |
115,650 |
2021-07-22 |
|
| 9 |
Mauro David J |
Chief Medical Officer |
95,000 |
2021-07-22 |
|
| 10 |
Morosini Deborah |
EVP, Chief of Clinical Affairs |
90,000 |
2022-02-17 |
|
| 11 |
Baker Bros. Advisors Lp |
10 Percent Owner |
76,000 |
2025-06-13 |
|
| 12 |
Babler Martin |
Director |
38,000 |
2025-06-13 |
|
| 13 |
Friedman Paul A |
Director |
38,000 |
2025-06-13 |
|
| 14 |
Dier Mardi |
Director |
38,000 |
2025-06-13 |
|
| 15 |
Bonita David P |
10 Percent Owner |
38,000 |
2025-06-13 |
|
| 16 |
Baker Brothers Life Sciences Lp |
Director |
34,300 |
2022-06-22 |
|
| 17 |
Huang Jane |
President, CMO |
18,750 |
2025-10-07 |
|
| 18 |
Pierce Christopher |
EVP and Chief of Business Oper |
3,750 |
2021-09-07 |
|
Recent Transactions (last 12 months)
| Date |
Name |
Role |
Type |
Shares |
Price |
Value |
| 2026-03-05 |
Brusky Sean P. |
Chief Business Officer |
Unknown |
275,000 |
- |
- |
| 2026-02-04 |
Combs Andrew |
Chief Chemistry Officer |
RSU Award |
230,000 |
$2.30 |
$529K |
| 2026-02-04 |
Vaddi Krishna |
CEO |
RSU Award |
837,000 |
$2.30 |
$1.93M |
| 2026-02-04 |
Scherle Peggy |
Chief Scientific Officer |
RSU Award |
230,000 |
$2.30 |
$529K |
| 2026-02-04 |
Lim Bryant David |
CLO, CFO, Corp Sec. |
RSU Award |
275,000 |
$2.30 |
$632.5K |
| 2025-11-05 |
Sandor Victor |
Director |
RSU Award |
121,285 |
$1.39 |
$168.59K |
| 2025-10-17 |
Dorton Katina |
Officer |
Unknown |
- |
- |
- |
| 2025-10-04 |
Huang Jane |
President, CMO |
Option Exercise (Sell) |
9,375 |
- |
- |
| 2025-07-04 |
Huang Jane |
President, CMO |
Option Exercise (Sell) |
9,375 |
- |
- |
| 2025-06-12 |
Scherer Paul C |
Officer |
Unknown |
- |
- |
- |
| 2025-06-12 |
Sandor Victor |
Director |
RSU Award |
38,000 |
$1.04 |
$39.52K |
| 2025-06-12 |
Dier Mardi |
Director |
RSU Award |
38,000 |
$1.04 |
$39.52K |
| 2025-06-12 |
Bonita David P |
10 Percent Owner |
RSU Award |
38,000 |
$1.04 |
$39.52K |
| 2025-06-12 |
Babler Martin |
Director |
RSU Award |
38,000 |
$1.04 |
$39.52K |
| 2025-06-12 |
Baker Bros. Advisors Lp |
10 Percent Owner |
RSU Award |
76,000 |
$1.04 |
$79.04K |
| 2025-06-12 |
Friedman Paul A |
Director |
RSU Award |
38,000 |
$1.04 |
$39.52K |
