Stoke Therapeutics, Inc. STOK NASDAQ

NASDAQ Global Select • Healthcare • Biotechnology • US • USD

SharesGrow Score

53/100

3/7 Pass

SharesGrow Intrinsic Value

Stoke Therapeutics, Inc. (STOK) has 20 known insider and institutional holders on record. The largest holder is Apple Tree Partners IV, L.P. with 17,161,713 shares. Other notable holders include Skorpios Trust and RTW INVESTMENTS, LP.

Over the last 12 months, insiders have made 55 transactions in STOK stock — 14 buys (valued at $1.95M) and 32 sells (valued at $33.52M). Insider selling has exceeded buying during this period.

STOK Insider Ownership

Top Holder

Apple Tree Partners IV, L.P.

17,161,713 shares

Buys (12 mo)

$1.95M value

Sells (12 mo)

$33.52M value

12-Month Transaction Activity

Buy 25%

Sell 58%

Top Insider Holders

#	Name	Role	Shares Owned	Last Filed	Relative Size
1	Apple Tree Partners Iv, L.p.	10 Percent Owner	17,161,713	2020-11-25	100%
2	Skorpios Trust	10 Percent Owner	3,906,181	2025-06-06	23%
3	Rtw Investments, Lp	10 Percent Owner	3,544,248	2019-11-12	21%
4	Krainer Adrian R.	Director	283,302	2026-03-12	2%
5	Smith Ian F	Chief Executive Officer	129,000	2026-02-19	1%
6	Walker Robin A.	Chief Legal Officer, Cco & Sec	60,000	2020-03-26	0%
7	Tulipano Stephen J	Former CFO	40,000	2024-06-07	0%
8	Nash Huw M.	COO & Cbo	40,000	2024-06-07	0%
9	Ticho Barry	Chief Medical Officer	38,864	2026-04-03	0%
10	Kaye Edward M. Md	Director	35,500	2026-03-17	0%
11	Tzianabos Arthur	Interim Executive Chair	31,339	2026-03-12	0%
12	Smith Julie	Director	29,747	2025-06-04	0%
13	Burstein Jennifer	Director	29,747	2025-06-04	0%
14	Harrison Seth Loring	Director	29,747	2025-06-04	0%
15	Menzel Garry E	Director	29,747	2025-06-04	0%
16	Hall Samuel W.	10 Percent Owner	29,555	2019-09-12	0%
17	Liau Gene	EVP Research & Preclinical Dev	21,351	2021-03-04	0%
18	Allan Jonathan	General Counsel & Corp Sec	19,543	2026-03-24	0%
19	Leggett Thomas	Chief Financial Officer	12,554	2026-03-19	0%
20	Hoitt Jason	Chief Patient Officer	12,207	2026-03-19	0%

Recent Transactions (last 12 months)

Date	Name	Role	Type	Shares	Price	Value
2026-04-01	Ticho Barry	Chief Medical Officer	Informative Sell	1,838	$32.66	$60.03K
2026-03-20	Allan Jonathan	General Counsel & Corp Sec	Informative Sell	601	$34.41	$20.68K
2026-03-18	Allan Jonathan	General Counsel & Corp Sec	Informative Sell	72	$32.85	$2.37K
2026-03-17	Allan Jonathan	General Counsel & Corp Sec	Informative Sell	1,791	$33.38	$59.78K
2026-03-19	Ticho Barry	Chief Medical Officer	Informative Sell	1,461	$29.99	$43.82K
2026-03-18	Ticho Barry	Chief Medical Officer	Informative Sell	103	$32.85	$3.38K
2026-03-17	Ticho Barry	Chief Medical Officer	Informative Sell	2,587	$33.38	$86.34K
2026-03-18	Leggett Thomas	Chief Financial Officer	Informative Sell	37	$32.85	$1.22K
2026-03-17	Leggett Thomas	Chief Financial Officer	Informative Sell	922	$33.38	$30.77K
2026-03-18	Hoitt Jason	Chief Patient Officer	Informative Sell	30	$32.85	$985.50
2026-03-17	Hoitt Jason	Chief Patient Officer	Informative Sell	748	$33.38	$24.96K
2026-03-15	Allan Jonathan	General Counsel & Corp Sec	Option Exercise (Sell)	7,475	-	-
2026-03-15	Ticho Barry	Chief Medical Officer	Option Exercise (Sell)	13,100	-	-
2026-03-15	Leggett Thomas	Chief Financial Officer	Option Exercise	14,750	-	-
2026-03-15	Hoitt Jason	Chief Patient Officer	Option Exercise	10,000	-	-
2026-03-15	Kaye Edward M. Md	Director	Option Exercise (Sell)	35,500	-	-
2026-03-13	Levin Arthur A	Director	Informative Sell	605	$36.80	$22.26K
2026-03-10	Krainer Adrian R.	Director	Informative Sell	33,243	$39.74	$1.32M
2026-03-10	Tzianabos Arthur	Interim Executive Chair	Informative Sell	4,355	$40.00	$174.21K
2026-03-02	Krainer Adrian R.	Director	Informative Sell	7,229	$39.66	$286.72K
2026-02-17	Allan Jonathan	General Counsel & Corp Sec	RSU Award	35,000	-	-
2026-02-17	Ticho Barry	Chief Medical Officer	RSU Award	40,000	-	-
2026-02-17	Leggett Thomas	Chief Financial Officer	RSU Award	40,000	-	-
2026-02-17	Hoitt Jason	Chief Patient Officer	RSU Award	48,000	-	-
2026-02-17	Smith Ian F	Chief Executive Officer	RSU Award	129,000	-	-