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Karyopharm Therapeutics Inc. KPTI NASDAQ

NASDAQ Global Select • Healthcare • Biotechnology • US • USD

SharesGrow Score
41/100
2/7 Pass
SharesGrow Intrinsic Value
N/A
Negative cash flow
Analyst Price Target
$14.17
+65.5%
SharesGrow 7-Criteria Score All 7 criteria scored · valuation-related highlighted on this page

Karyopharm Therapeutics Inc. (KPTI) has a negative trailing P/E of -0.7, meaning the company is currently unprofitable on a trailing twelve-month (TTM) basis. The forward P/E of 2.4 based on analyst estimates suggests a return to profitability is expected. Trailing earnings yield is -140.55%, forward earnings yield 40.98%. PEG 0.03 (Peter Lynch undervalued ≤1.0).

Criteria proven by this page:

  • VALUE (100/100, Pass) — PEG ≤ 1.0 — Peter Lynch undervalued (0.03); analyst target implies upside (+65.5%).
  • Forward P/E 2.4 — analysts expect a return to profitability with estimated EPS of $3.51 for FY2029.
  • PEG Ratio 0.03 — below 1.0 suggests the stock is undervalued relative to its earnings growth rate (Peter Lynch criterion).
  • Trailing Earnings Yield -140.55% — negative yield confirms the company is currently unprofitable. Investors are paying for a turnaround rather than current earnings. Forward yield improves to 40.98% as earnings recover.
  • Analyst consensus target $14.17 (+65.5% upside) — significant upside potential according to Wall Street analysts.

Overall SharesGrow Score: 41/100 with 2/7 criteria passed.

SharesGrow 7-Criteria Score
41/100
SG Score
View full scorecard →
VALUE
100/100
Price-to-Earnings & upside
Proven by this page
FUTURE
85/100
Analyst consensus
→ Forecast
PAST
0/100
→ Income
HEALTH
25/100
Debt-to-Equity & liquidity
→ Health
~
MOAT
54/100
→ Income
GROWTH
15/100
→ Income
INCOME
10/100
→ Income

Valuation Snapshot — KPTI

Valuation Multiples
P/E (TTM)-0.7
Forward P/E2.4
PEG Ratio0.03
Forward PEG0.03
P/B Ratio-0.48
P/S Ratio0.45
EV/EBITDA-3.0
Per Share Data
EPS (TTM)$-10.91
Forward EPS (Est.)$3.51
Book Value / Share$-16.30
Revenue / Share$8.13
FCF / Share$-4.19
Yields & Fair Value
Earnings Yield-140.55%
Forward Earnings Yield40.98%
Dividend Yield0.00%
Analyst Target$14.17 (+65.5%)

Historical Valuation

Year P/E (TTM) PEG Ratio P/B Ratio P/S Ratio Dividend Yield
2016 -3.2 0.27 2.17 2,287.93 -
2017 -3.4 0.91 3.40 274.25 -
2018 -3.0 -0.25 2.90 17.53 -
2019 -5.9 -2.32 23.84 29.01 -
2020 -5.7 0.37 22.04 10.30 -
2021 -3.9 0.10 -6.06 2.30 -
2022 -1.7 -0.08 -16.71 1.77 -
2023 -0.7 0.02 -0.73 0.68 -
2024 -1.1 0.02 -0.44 0.57 -
2025 -0.4 0.00 -0.27 0.55 -

EPS: Actual vs Estimates

P/E Ratio & Earnings Yield

Earnings Per Share (EPS) History

Year EPS (Diluted) Revenue Net Income Net Margin
2016 $-2.92 $154K $-109.58M -71153.9%
2017 $-2.81 $1.61M $-128.98M -8036.4%
2018 $-3.14 $30.34M $-178.41M -588.1%
2019 $-3.22 $40.89M $-199.59M -488.1%
2020 $-2.72 $108.09M $-196.27M -181.6%
2021 $-1.65 $209.82M $-124.09M -59.1%
2022 $-2.02 $157.07M $-165.29M -105.2%
2023 $-1.25 $146.03M $-143.1M -98%
2024 $-1.23 $145.24M $-76.42M -52.6%
2025 $-17.93 $146.07M $-196.04M -134.2%

Analyst Estimates

Year EPS (Avg) EPS Range Revenue (Avg) Revenue Range Analysts
2026 $-4.45 $-6.02 – $-3.07 $137.49M $127.98M – $155.34M 4
2027 $-3.20 $-5.35 – $-1.05 $168.23M $149.7M – $186.76M 3
2028 $-1.21 $-2.24 – $-0.34 $216.08M $216.03M – $216.13M 3
2029 $3.58 $3.14 – $4.17 $352.31M $318.53M – $397.07M 1
2030 $6.98 $6.11 – $8.13 $505.43M $456.97M – $569.64M 1
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