There have been 50 recent insider transactions recorded for Spero Therapeutics, Inc. (SPRO), including 26 buys and 24 sells. Total insider buying was valued at $1.42M and total insider selling at $925.35K.
Notable insiders with recent activity include Keutzer Timothy, Rajavelu Esther, Mahadevia Ankit. Insider transactions can provide insights into how company leadership views the stock's valuation and future prospects.
Insider Transactions — SPRO
| Date |
Name |
Role |
Transaction |
Shares |
Avg. Price |
Value |
Shares Owned |
| 2026-02-06 |
Keutzer Timothy |
Chief Operating Officer |
Informative Sell |
18,652 |
$2.36 |
$44.02K |
742,506 |
| 2026-02-06 |
Rajavelu Esther |
See Remarks |
Informative Sell |
50,816 |
$2.36 |
$119.93K |
1,012,091 |
| 2026-02-04 |
Keutzer Timothy |
Chief Operating Officer |
Informative Sell |
3,471 |
$2.24 |
$7.78K |
761,158 |
| 2026-02-03 |
Keutzer Timothy |
Chief Operating Officer |
Informative Sell |
24,224 |
$2.14 |
$51.84K |
764,629 |
| 2026-02-02 |
Rajavelu Esther |
See Remarks |
RSU Award |
498,000 |
$2.23 |
$1.11M |
498,000 |
| 2026-02-02 |
Keutzer Timothy |
Chief Operating Officer |
RSU Award |
137,000 |
$2.23 |
$305.51K |
137,000 |
| 2025-11-07 |
Rajavelu Esther |
See Remarks |
Informative Sell |
40,270 |
$2.37 |
$95.44K |
869,450 |
| 2025-08-28 |
Mahadevia Ankit |
Director |
Informative Sell |
6,572 |
$1.97 |
$12.95K |
703,294 |
| 2025-08-28 |
Keutzer Timothy |
Chief Operating Officer |
Informative Sell |
1,695 |
$1.97 |
$3.34K |
739,744 |
| 2025-06-12 |
Thomas Frank E |
Director |
RSU Award |
20,000 |
- |
- |
75,000 |
| 2025-06-12 |
Pottage John C Jr |
Director |
RSU Award |
20,000 |
- |
- |
75,000 |
| 2025-06-12 |
Deshpande Milind |
Director |
RSU Award |
20,000 |
- |
- |
91,454 |
| 2025-06-12 |
Vink Patrick V.j.j. |
Director |
RSU Award |
20,000 |
- |
- |
75,000 |
| 2025-06-12 |
Jackson Scott Thomas |
Director |
RSU Award |
20,000 |
- |
- |
75,000 |
| 2025-06-12 |
Smith Cynthia |
Director |
RSU Award |
20,000 |
- |
- |
75,000 |
| 2025-06-12 |
Mahadevia Ankit |
Director |
RSU Award |
20,000 |
- |
- |
709,866 |
| 2025-06-12 |
Tregoning Kathleen |
Director |
RSU Award |
20,000 |
- |
- |
75,000 |
| 2025-05-02 |
Rajavelu Esther |
See Remarks |
RSU Award |
185,000 |
- |
- |
909,720 |
| 2025-02-05 |
Mahadevia Ankit |
Director |
Informative Sell |
55,260 |
$0.78 |
$43.1K |
689,866 |
| 2025-02-05 |
Shukla Sath |
CEO & President |
Informative Sell |
106,408 |
$0.78 |
$83K |
1,736,883 |
| 2025-02-05 |
Keutzer Timothy |
Chief Operating Officer |
Informative Sell |
24,920 |
$0.78 |
$19.44K |
741,439 |
| 2025-02-05 |
Rajavelu Esther |
CFO & Cbo |
Informative Sell |
20,689 |
$0.78 |
$16.14K |
724,720 |
| 2025-02-03 |
Shukla Sath |
CEO & President |
RSU Award |
751,407 |
- |
- |
1,892,216 |
| 2025-02-03 |
Keutzer Timothy |
Chief Operating Officer |
RSU Award |
266,139 |
- |
- |
797,976 |
| 2025-02-03 |
Rajavelu Esther |
CFO & Cbo |
RSU Award |
266,139 |
- |
- |
645,409 |
| 2024-11-08 |
Rajavelu Esther |
CFO & Cbo |
Informative Sell |
17,245 |
$1.30 |
$22.42K |
379,270 |
| 2024-11-07 |
Rajavelu Esther |
CFO & Cbo |
Informative Sell |
23,351 |
$1.31 |
$30.59K |
396,515 |
| 2024-08-27 |
Mahadevia Ankit |
Director |
Informative Sell |
5,912 |
$1.35 |
$7.98K |
759,085 |
| 2024-08-27 |
Shukla Sath |
CEO & President |
Informative Sell |
2,757 |
$1.35 |
$3.72K |
1,140,809 |
| 2024-08-27 |
Keutzer Timothy |
Chief Operating Officer |
Informative Sell |
2,213 |
$1.35 |
$2.99K |
531,837 |
| 2024-08-05 |
Shukla Sath |
CEO and President |
Informative Sell |
17,641 |
$1.31 |
$23.11K |
1,143,566 |
| 2024-08-02 |
Shukla Sath |
CEO and President |
Informative Sell |
14,800 |
$1.32 |
$19.54K |
1,161,207 |
| 2024-05-29 |
Thomas Frank E |
Director |
RSU Award |
20,000 |
- |
- |
55,000 |
| 2024-05-29 |
Pottage John C Jr |
Director |
RSU Award |
20,000 |
- |
- |
55,000 |
| 2024-05-29 |
Deshpande Milind |
Director |
RSU Award |
20,000 |
- |
- |
71,454 |
| 2024-05-29 |
Vink Patrick V.j.j. |
Director |
RSU Award |
20,000 |
- |
- |
55,000 |
| 2024-05-29 |
Jackson Scott Thomas |
Director |
RSU Award |
20,000 |
- |
- |
55,000 |
| 2024-05-29 |
Smith Cynthia |
Director |
RSU Award |
20,000 |
- |
- |
55,000 |
| 2024-05-29 |
Mahadevia Ankit |
Director |
RSU Award |
20,000 |
- |
- |
764,997 |
| 2024-05-29 |
Tregoning Kathleen |
Director |
RSU Award |
20,000 |
- |
- |
55,000 |
| 2024-02-05 |
Shukla Sath |
CEO and President |
Informative Sell |
45,093 |
$1.45 |
$65.38K |
1,176,007 |
| 2024-02-02 |
Joseph Tamara L |
Chief Legal Officer |
Informative Sell |
30,906 |
$1.37 |
$42.34K |
531,615 |
| 2024-02-02 |
Mahadevia Ankit |
Director |
Informative Sell |
63,795 |
$1.37 |
$87.4K |
744,997 |
| 2024-02-02 |
Shukla Sath |
CEO and President |
Informative Sell |
30,901 |
$1.37 |
$42.33K |
1,221,100 |
| 2024-02-02 |
Keutzer Timothy |
Chief Operating Officer |
Informative Sell |
30,971 |
$1.36 |
$42.12K |
534,050 |
| 2024-02-02 |
Hamed Kamal |
Chief Medical Officer |
Informative Sell |
28,075 |
$1.37 |
$38.46K |
788,117 |
| 2024-02-01 |
Joseph Tamara L |
Chief Legal Officer |
RSU Award |
239,731 |
- |
- |
562,521 |
| 2024-02-01 |
Shukla Sath |
CEO and President |
RSU Award |
679,501 |
- |
- |
1,252,001 |
| 2024-02-01 |
Keutzer Timothy |
Chief Operating Officer |
RSU Award |
239,731 |
- |
- |
565,021 |
| 2024-02-01 |
Rajavelu Esther |
See Remarks |
RSU Award |
119,866 |
- |
- |
419,866 |
■ Informative Buy/Sell — open market transaction (most significant)
■ Uninformative Buy — award, option exercise, conversion
■ Uninformative Sell — tax withholding, award vest sale
■ Neutral — gift, trust, expiry
