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Spero Therapeutics, Inc. SPRO NASDAQ

NASDAQ Global Select • Healthcare • Biotechnology • US • USD

SharesGrow Score
61/100
2/7 Pass
SharesGrow Intrinsic Value
$7.22
+159.7%
SharesGrow 7-Criteria Score All 7 criteria scored · valuation-related highlighted on this page

Spero Therapeutics, Inc. (SPRO) trades at a trailing P/E of 17.9, forward P/E of 4.2. Trailing earnings yield is 5.59%, forward earnings yield 24.10%. PEG 0.01 (Peter Lynch undervalued ≤1.0). Graham Number is $1.90.

Criteria proven by this page:

  • VALUE (93/100, Pass) — P/E is below market average (17.9); PEG ≤ 1.0 — Peter Lynch undervalued (0.01); earnings yield beats bond yields (5.59%).
  • Forward P/E 4.2 (down from trailing 17.9) — analysts expect earnings to grow, which would improve the valuation.
  • PEG Ratio 0.01 — below 1.0 suggests the stock is undervalued relative to its earnings growth rate (Peter Lynch criterion).
  • Trailing Earnings Yield 5.59% — exceeds typical bond yields (~4.3%), making equity attractive vs fixed income. Forward yield improves to 24.10% as earnings recover.

Overall SharesGrow Score: 61/100 with 2/7 criteria passed.

SharesGrow 7-Criteria Score
61/100
SG Score
View full scorecard →
VALUE
93/100
Price-to-Earnings & upside
Proven by this page
FUTURE
20/100
Analyst consensus
→ Forecast
~
PAST
50/100
→ Income
HEALTH
100/100
Debt-to-Equity & liquidity
→ Health
~
MOAT
50/100
→ Income
~
GROWTH
58/100
→ Income
~
INCOME
55/100
→ Income

Valuation Snapshot — SPRO

Valuation Multiples
P/E (TTM)17.9
Forward P/E4.2
PEG Ratio0.01
Forward PEG0.01
P/B Ratio2.60
P/S Ratio2.62
EV/EBITDA22.1
Per Share Data
EPS (TTM)$0.15
Forward EPS (Est.)$0.67
Book Value / Share$1.05
Revenue / Share$1.08
FCF / Share$-0.23
Yields & Fair Value
Earnings Yield5.59%
Forward Earnings Yield24.10%
Dividend Yield0.00%
Graham Number$1.90
SharesGrow IV$7.22 (+159.7%)

Historical Valuation

Year P/E (TTM) PEG Ratio P/B Ratio P/S Ratio Dividend Yield
2016 -3.0 -0.02 7.47 226.73 -
2017 -0.7 0.00 0.36 15.36 -
2018 -2.4 0.03 0.85 24.81 -
2019 -2.9 -0.11 2.34 9.63 -
2020 -5.5 -0.87 3.29 46.52 -
2021 -5.5 0.32 5.60 161.12 -
2022 -1.4 0.02 0.86 1.34 -
2023 3.4 -0.03 0.72 0.75 -
2024 -0.8 0.00 1.21 1.16 -
2025 15.2 -0.14 2.21 2.19 -

EPS: Actual vs Estimates

P/E Ratio & Earnings Yield

Earnings Per Share (EPS) History

Year EPS (Diluted) Revenue Net Income Net Margin
2016 $-3.86 $335K $-25.49M -7609.3%
2017 $-17.82 $1.98M $-46.1M -2329.3%
2018 $-2.60 $3.97M $-41.66M -1050.5%
2019 $-3.31 $4.74M $-60.18M -1269%
2020 $-3.46 $9.33M $-77.52M -830.9%
2021 $-2.96 $18.26M $-91.3M -500.1%
2022 $-1.28 $48.58M $-48.03M -98.9%
2023 $0.43 $96.74M $22.81M 23.6%
2024 $-1.27 $27.4M $-68.57M -250.3%
2025 $0.15 $59.62M $8.57M 14.4%

Analyst Estimates

Year EPS (Avg) EPS Range Revenue (Avg) Revenue Range Analysts
2026 $0.67 $0.67 – $0.67 $800K $800K – $800K 1
2027 $-0.68 $-0.68 – $-0.68 $3.2M $3.2M – $3.2M 1
2028 $-0.12 $-0.12 – $-0.12 $33.1M $33.1M – $33.1M 1
2029 $0.75 $0.75 – $0.75 $99.1M $99.1M – $99.1M 1
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