Protagonist Therapeutics, Inc. (PTGX) has 20 known insider and institutional holders on record. The largest holder is CANAAN X L.P. with 2,116,552 shares. Other notable holders include ADAGE CAPITAL PARTNERS GP, L.L.C. and PATEL DINESH V PH D.
Over the last 12 months, insiders have made 44 transactions in PTGX stock — 9 buys (valued at $17.89M) and 13 sells (valued at $10.23M). Insider selling has exceeded buying during this period.
PTGX Insider Ownership
Top Holder
CANAAN X L.P.
2,116,552 shares
Buys (12 mo)
9
$17.89M value
Sells (12 mo)
13
$10.23M value
12-Month Transaction Activity
Top Insider Holders
| # |
Name |
Role |
Shares Owned |
Last Filed |
Relative Size |
| 1 |
Canaan X L.p. |
10 Percent Owner |
2,116,552 |
2018-05-21 |
|
| 2 |
Adage Capital Partners Gp, L.l.c. |
10 Percent Owner |
2,056,076 |
2017-06-01 |
|
| 3 |
Patel Dinesh V Ph D |
President and CEO |
524,938 |
2026-03-25 |
|
| 4 |
Gupta Suneel |
Chief Development Officer |
93,300 |
2024-11-27 |
|
| 5 |
Liu David Y |
Chief Scientific Officer |
66,538 |
2022-03-02 |
|
| 6 |
Hodder William A |
Sr. VP - Corporate Development |
65,000 |
2016-10-13 |
|
| 7 |
Molina Arturo Md |
Chief Medical Officer |
50,971 |
2026-03-27 |
|
| 8 |
Swisher Daniel N Jr |
Director |
45,000 |
2023-10-30 |
|
| 9 |
Shames Richard S. |
Chief Medical Officer |
32,678 |
2019-03-04 |
|
| 10 |
Noonberg Sarah B. |
Director |
30,000 |
2023-01-18 |
|
| 11 |
Kalkofen Donald A. |
Chief Financial Officer |
18,521 |
2022-02-17 |
|
| 12 |
Khosla Chaitan Phd |
Director |
15,000 |
2020-05-29 |
|
| 13 |
O'neil Thomas P. |
Chief Financial Officer |
14,050 |
2018-08-17 |
|
| 14 |
Saks Samuel R |
Chief Medical Officer |
14,000 |
2021-02-26 |
|
| 15 |
Ali Asif |
Chief Financial Officer |
13,282 |
2026-03-27 |
|
| 16 |
Papanek Julie |
Director |
12,000 |
2017-05-26 |
|
| 17 |
Shanafelt Armen |
10 Percent Owner |
12,000 |
2018-06-12 |
|
| 18 |
Williams Lewis T |
Director |
6,000 |
2026-02-18 |
|
| 19 |
Selick Harold E |
Director |
3,762 |
2026-01-06 |
|
| 20 |
Waddill William D. |
Director |
3,762 |
2026-01-06 |
|
Recent Transactions (last 12 months)
| Date |
Name |
Role |
Type |
Shares |
Price |
Value |
| 2026-03-26 |
Ali Asif |
Chief Financial Officer |
Option Exercise (Sell) |
5,265 |
$12.17 |
$64.08K |
| 2026-03-26 |
Molina Arturo Md |
Chief Medical Officer |
Option Exercise (Sell) |
15,000 |
$8.04 |
$120.6K |
| 2026-03-26 |
Selick Harold E |
Director |
Option Exercise (Sell) |
24,000 |
$12.88 |
$309.12K |
| 2026-03-25 |
Patel Dinesh V Ph D |
President and CEO |
Option Exercise (Sell) |
54,641 |
$8.58 |
$468.82K |
| 2026-03-24 |
Patel Dinesh V Ph D |
President and CEO |
Option Exercise (Sell) |
59 |
$8.58 |
$506.22 |
| 2026-03-23 |
Patel Dinesh V Ph D |
President and CEO |
Gift (Given) |
50,000 |
- |
- |
| 2026-02-17 |
Williams Lewis T |
Director |
Option Exercise |
18,000 |
$10.84 |
$195.12K |
| 2026-02-06 |
Waddill William D. |
Director |
Option Exercise (Sell) |
20,000 |
$8.31 |
$166.2K |
| 2026-01-27 |
Ali Asif |
Chief Financial Officer |
Option Exercise (Sell) |
12,000 |
$12.17 |
$146.04K |
| 2026-01-27 |
Molina Arturo Md |
Chief Medical Officer |
Option Exercise (Sell) |
5,000 |
$8.04 |
$40.2K |
| 2026-01-26 |
Molina Arturo Md |
Chief Medical Officer |
Option Exercise (Sell) |
5,000 |
$8.04 |
$40.2K |
| 2026-01-23 |
Molina Arturo Md |
Chief Medical Officer |
Informative Sell |
13,151 |
$82.42 |
$1.08M |
| 2026-01-27 |
Patel Dinesh V Ph D |
President and CEO |
Option Exercise (Sell) |
4,068 |
$21.58 |
$87.79K |
| 2026-01-26 |
Patel Dinesh V Ph D |
President and CEO |
Option Exercise (Sell) |
10,685 |
$4.21 |
$44.98K |
| 2026-01-23 |
Patel Dinesh V Ph D |
President and CEO |
Option Exercise (Sell) |
19,315 |
$4.21 |
$81.32K |
| 2026-01-20 |
Ali Asif |
Chief Financial Officer |
Informative Sell |
8,588 |
$82.48 |
$708.34K |
| 2026-01-20 |
Molina Arturo Md |
Chief Medical Officer |
Informative Sell |
9,514 |
$82.48 |
$784.71K |
| 2026-01-20 |
Patel Dinesh V Ph D |
President and CEO |
Informative Sell |
34,438 |
$82.48 |
$2.84M |
| 2026-01-09 |
Selick Harold E |
Director |
Option Exercise (Sell) |
14,299 |
$4.21 |
$60.2K |
| 2026-01-02 |
Ali Asif |
Chief Financial Officer |
RSU Award |
32,000 |
$87.18 |
$2.79M |
| 2026-01-02 |
Giraudo Bryan |
Director |
RSU Award |
3,762 |
$87.18 |
$327.97K |
| 2026-01-02 |
Waddill William D. |
Director |
RSU Award |
3,762 |
$87.18 |
$327.97K |
| 2026-01-02 |
Williams Lewis T |
Director |
RSU Award |
3,762 |
$87.18 |
$327.97K |
| 2026-01-02 |
O'dowd Sarah A |
Director |
RSU Award |
3,762 |
$87.18 |
$327.97K |
| 2026-01-02 |
Molina Arturo Md |
Chief Medical Officer |
RSU Award |
32,000 |
$87.18 |
$2.79M |
