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Protagonist Therapeutics, Inc. PTGX NASDAQ

NASDAQ Global Market • Healthcare • Biotechnology • US • USD

SharesGrow Score
67/100
4/7 Pass
SharesGrow Intrinsic Value
$28.60
-72.7%
Analyst Price Target
$113.60
+8.5%
SharesGrow 7-Criteria Score All 7 criteria scored · valuation-related highlighted on this page

Protagonist Therapeutics, Inc. (PTGX) has a negative trailing P/E of -50.4, meaning the company is currently unprofitable on a trailing twelve-month (TTM) basis. The forward P/E of 32.4 based on analyst estimates suggests a return to profitability is expected. Trailing earnings yield is -1.99%, forward earnings yield 3.09%. PEG 3.41.

Criteria proven by this page:

  • VALUE (88/100, Pass) — composite valuation score exceeds the 60/100 pass threshold.
  • Forward P/E 32.4 — analysts expect a return to profitability with estimated EPS of $3.23 for FY2026.
  • PEG Ratio 3.41 — above 2.0 suggests expensive relative to earnings growth.
  • Trailing Earnings Yield -1.99% — negative yield confirms the company is currently unprofitable. Investors are paying for a turnaround rather than current earnings. Forward yield improves to 3.09% as earnings recover.
  • Analyst consensus target $113.60 (+8.5% upside) — modest upside expected.

Overall SharesGrow Score: 67/100 with 4/7 criteria passed.

SharesGrow 7-Criteria Score
67/100
SG Score
View full scorecard →
VALUE
88/100
Price-to-Earnings & upside
Proven by this page
FUTURE
88/100
Analyst consensus
→ Forecast
PAST
25/100
→ Income
HEALTH
100/100
Debt-to-Equity & liquidity
→ Health
~
MOAT
58/100
→ Income
GROWTH
100/100
→ Income
INCOME
10/100
→ Income

Valuation Snapshot — PTGX

Valuation Multiples
P/E (TTM)-50.4
Forward P/E32.4
PEG Ratio3.41
Forward PEG3.41
P/B Ratio10.66
P/S Ratio142.99
EV/EBITDA-45.1
Per Share Data
EPS (TTM)$-2.05
Forward EPS (Est.)$3.23
Book Value / Share$9.67
Revenue / Share$0.72
FCF / Share$0.91
Yields & Fair Value
Earnings Yield-1.99%
Forward Earnings Yield3.09%
Dividend Yield0.00%
SharesGrow IV$28.60 (-72.7%)
Analyst Target$113.60 (+8.5%)

Historical Valuation

Year P/E (TTM) PEG Ratio P/B Ratio P/S Ratio Dividend Yield
2016 -3.8 -0.03 -2.21 0.00 -
2017 -10.0 0.16 -3.62 18.34 -
2018 -3.9 0.23 -1.07 4.87 -
2019 -2.4 -0.03 2.28 790.27 -
2020 -10.5 0.29 2.48 24.22 -
2021 -12.6 -0.33 5.28 57.91 -
2022 -4.2 0.86 2.48 20.13 -
2023 -16.5 0.37 3.87 21.69 -
2024 8.6 -0.02 3.52 5.47 -
2025 -42.7 0.29 9.03 120.66 -

EPS: Actual vs Estimates

P/E Ratio & Earnings Yield

Earnings Per Share (EPS) History

Year EPS (Diluted) Revenue Net Income Net Margin
2016 $-5.72 $0.00 $-37.18M -
2017 $-2.09 $20.06M $-36.96M -184.2%
2018 $-1.74 $30.93M $-38.92M -125.9%
2019 $-2.98 $231K $-77.19M -33414.3%
2020 $-1.92 $28.63M $-66.15M -231.1%
2021 $-2.65 $27.36M $-122.63M -448.2%
2022 $-2.52 $26.58M $-123.41M -464.3%
2023 $-1.39 $60M $-78.96M -131.6%
2024 $4.23 $434.43M $275.19M 63.3%
2025 $-2.05 $46.02M $-130.15M -282.8%

Analyst Estimates

Year EPS (Avg) EPS Range Revenue (Avg) Revenue Range Analysts
2026 $3.23 $-9.28 – $14.86 $441.4M $31.46M – $717.21M 8
2027 $-0.68 $-1.13 – $-0.09 $155.59M $85.83M – $304.98M 7
2028 $1.56 $-7.56 – $10.54 $303.31M $39.08M – $524.47M 6
2029 $2.57 $-0.34 – $5.00 $419.23M $54.01M – $724.91M 4
2030 $4.65 $-0.62 – $9.05 $601.88M $77.54M – $1.04B 2
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