There have been 50 recent insider transactions recorded for Denali Therapeutics Inc. (DNLI), including 15 buys and 31 sells. Total insider buying was valued at $18.74M and total insider selling at $6.73M.
Notable insiders with recent activity include Watts Ryan J., Schuth Alexander O., Baker Bros. Advisors Lp. Insider transactions can provide insights into how company leadership views the stock's valuation and future prospects.
Insider Transactions — DNLI
| Date |
Name |
Role |
Transaction |
Shares |
Avg. Price |
Value |
Shares Owned |
| 2026-01-06 |
Watts Ryan J. |
President and CEO |
Informative Sell |
35,198 |
$16.50 |
$580.77K |
296,833 |
| 2026-01-06 |
Schuth Alexander O. |
Cofo and Secretary |
Informative Sell |
17,218 |
$16.50 |
$284.1K |
282,828 |
| 2026-01-03 |
Watts Ryan J. |
President and CEO |
RSU Award |
236,880 |
$16.27 |
$3.85M |
236,880 |
| 2026-01-03 |
Schuth Alexander O. |
Cofo and Secretary |
RSU Award |
173,100 |
$16.27 |
$2.82M |
173,100 |
| 2025-12-11 |
Baker Bros. Advisors Lp |
Director |
Informative Buy |
190,523 |
$0.01 |
$1.91K |
2,335,469 |
| 2025-11-04 |
Van Hauwermeiren Timothy |
Director |
Unknown |
- |
- |
- |
- |
| 2025-11-04 |
Van Hauwermeiren Timothy |
Director |
RSU Award |
10,632 |
- |
- |
10,632 |
| 2025-09-03 |
Watts Ryan J. |
President and CEO |
Gift (Given) |
50,000 |
- |
- |
2,152,604 |
| 2025-08-13 |
Ho Carole |
Chief Medical Officer |
Informative Sell |
806 |
$14.64 |
$11.8K |
216,585 |
| 2025-08-12 |
Schuth Alexander O. |
Cofo and Secretary |
Informative Sell |
2,937 |
$13.58 |
$39.88K |
242,346 |
| 2025-08-12 |
Ho Carole |
Chief Medical Officer |
Informative Sell |
2,937 |
$13.58 |
$39.88K |
217,391 |
| 2025-08-05 |
Ho Carole |
Chief Medical Officer |
Option Exercise (Sell) |
44,655 |
$0.68 |
$30.37K |
62,500 |
| 2025-07-09 |
Watts Ryan J. |
President and CEO |
Option Exercise (Sell) |
40,000 |
$5.28 |
$211.2K |
20,369 |
| 2025-06-03 |
Baker Julian |
Officer |
Unknown |
- |
- |
- |
- |
| 2025-06-03 |
Flatley Jay T |
Director |
RSU Award |
6,037 |
- |
- |
16,220 |
| 2025-06-03 |
Baker Bros. Advisors Lp |
Director |
Unknown |
23,901,119 |
$0.01 |
$239.01K |
- |
| 2025-06-03 |
Baker Bros. Advisors Lp |
Director |
RSU Award |
31,695 |
$13.93 |
$441.51K |
31,695 |
| 2025-06-03 |
Tessier-lavigne Marc |
Director |
RSU Award |
18,111 |
$13.93 |
$252.29K |
18,111 |
| 2025-06-03 |
Klein Peter S |
Director |
RSU Award |
18,111 |
$13.93 |
$252.29K |
18,111 |
| 2025-06-03 |
Schenkein David P |
Director |
RSU Award |
6,037 |
- |
- |
15,257 |
| 2025-06-03 |
Krognes Steve E. |
Director |
RSU Award |
18,111 |
$13.93 |
$252.29K |
18,111 |
| 2025-06-03 |
Cook Jennifer E. |
Director |
RSU Award |
18,111 |
$13.93 |
$252.29K |
18,111 |
| 2025-06-03 |
Thornberry Nancy |
Director |
RSU Award |
18,111 |
$13.93 |
$252.29K |
18,111 |
| 2025-01-07 |
Krognes Steve E. |
Director |
Informative Sell |
3,339 |
$20.81 |
$69.48K |
25,757 |
| 2025-01-07 |
Watts Ryan J. |
President and CEO |
Informative Sell |
7,650 |
$20.81 |
$159.2K |
253,071 |
| 2025-01-07 |
Schuth Alexander O. |
Cofo and Secretary |
Informative Sell |
2,907 |
$20.81 |
$60.49K |
244,308 |
| 2025-01-07 |
Ho Carole |
Chief Medical Officer |
Informative Sell |
2,907 |
$20.81 |
$60.49K |
175,673 |
| 2025-01-06 |
Watts Ryan J. |
President and CEO |
Informative Sell |
29,266 |
$20.22 |
$591.76K |
260,721 |
| 2025-01-06 |
Schuth Alexander O. |
Cofo and Secretary |
Informative Sell |
12,255 |
$20.22 |
$247.8K |
247,215 |
| 2025-01-06 |
Ho Carole |
Chief Medical Officer |
Informative Sell |
12,255 |
$20.22 |
$247.8K |
178,580 |
| 2025-01-03 |
Watts Ryan J. |
President and CEO |
RSU Award |
162,540 |
$21.26 |
$3.46M |
162,540 |
| 2025-01-03 |
Schuth Alexander O. |
Cofo and Secretary |
RSU Award |
162,540 |
$21.26 |
$3.46M |
162,540 |
| 2025-01-03 |
Ho Carole |
Chief Medical Officer |
RSU Award |
162,540 |
$21.26 |
$3.46M |
162,540 |
| 2025-01-02 |
Sato Vicki L |
Director |
Informative Sell |
3,080 |
$20.91 |
$64.4K |
107,976 |
| 2024-12-31 |
Krognes Steve E. |
Director |
Informative Sell |
30,000 |
$20.25 |
$607.5K |
29,096 |
| 2024-12-27 |
Schuth Alexander O. |
Cofo and Secretary |
Option Exercise (Sell) |
6,708 |
$5.28 |
$35.42K |
46,671 |
| 2024-11-25 |
Ho Carole |
Chief Medical Officer |
Option Exercise (Sell) |
17,845 |
$0.68 |
$12.13K |
107,155 |
| 2024-11-22 |
Schuth Alexander O. |
Cofo and Secretary |
Option Exercise (Sell) |
20,516 |
$0.68 |
$13.95K |
124,562 |
| 2024-11-11 |
Schenkein David P |
Director |
Option Exercise (Sell) |
47,165 |
$18.00 |
$848.97K |
- |
| 2024-11-07 |
Sato Vicki L |
Director |
Informative Sell |
1,020 |
$30.00 |
$30.6K |
111,056 |
| 2024-11-07 |
Schuth Alexander O. |
Cofo and Secretary |
Option Exercise (Sell) |
15,558 |
$5.28 |
$82.15K |
53,379 |
| 2024-11-01 |
Sato Vicki L |
Director |
Informative Sell |
3,080 |
$27.07 |
$83.38K |
112,076 |
| 2024-10-18 |
Watts Ryan J. |
President and CEO |
Informative Sell |
40,000 |
$27.69 |
$1.11M |
235,807 |
| 2024-09-30 |
Krognes Steve E. |
Director |
Informative Sell |
30,000 |
$29.03 |
$870.9K |
29,096 |
| 2024-09-13 |
Sato Vicki L |
Director |
Informative Sell |
1,020 |
$30.00 |
$30.6K |
115,156 |
| 2024-09-03 |
Sato Vicki L |
Director |
Informative Sell |
100 |
$25.37 |
$2.54K |
116,176 |
| 2024-08-21 |
Schuth Alexander O. |
Cofo and Secretary |
Informative Sell |
2,547 |
$24.78 |
$63.11K |
178,066 |
| 2024-08-21 |
Ho Carole |
Chief Medical Officer |
Informative Sell |
5,907 |
$24.96 |
$147.44K |
118,810 |
| 2024-08-20 |
Krognes Steve E. |
Director |
Informative Sell |
1,727 |
$23.79 |
$41.09K |
32,677 |
| 2024-08-20 |
Watts Ryan J. |
President and CEO |
Informative Sell |
2,260 |
$23.79 |
$53.77K |
235,807 |
■ Informative Buy/Sell — open market transaction (most significant)
■ Uninformative Buy — award, option exercise, conversion
■ Uninformative Sell — tax withholding, award vest sale
■ Neutral — gift, trust, expiry
