Intrinsic Value of S&P & Nasdaq Contact Us

Ionis Pharmaceuticals, Inc. IONS NASDAQ

NASDAQ Global Select • Healthcare • Biotechnology • US • USD

SharesGrow Score
46/100
3/7 Pass
SharesGrow Intrinsic Value
N/A
Negative cash flow
Analyst Price Target
$96.40
+25.6%
SharesGrow 7-Criteria Score All 7 criteria scored · valuation-related highlighted on this page

Ionis Pharmaceuticals, Inc. (IONS) has a negative trailing P/E of -32.1, meaning the company is currently unprofitable on a trailing twelve-month (TTM) basis. The forward P/E of 65.9 based on analyst estimates suggests a return to profitability is expected. Trailing earnings yield is -3.11%, forward earnings yield 1.52%. PEG 0.51 (Peter Lynch undervalued ≤1.0).

Criteria proven by this page:

  • VALUE (92/100, Pass) — PEG ≤ 1.0 — Peter Lynch undervalued (0.51); analyst target implies upside (+25.6%).
  • Forward P/E 65.9 — analysts expect a return to profitability with estimated EPS of $1.17 for FY2028.
  • PEG Ratio 0.51 — below 1.0 suggests the stock is undervalued relative to its earnings growth rate (Peter Lynch criterion).
  • Trailing Earnings Yield -3.11% — negative yield confirms the company is currently unprofitable. Investors are paying for a turnaround rather than current earnings. Forward yield improves to 1.52% as earnings recover.
  • Analyst consensus target $96.40 (+25.6% upside) — significant upside potential according to Wall Street analysts.

Overall SharesGrow Score: 46/100 with 3/7 criteria passed.

SharesGrow 7-Criteria Score
46/100
SG Score
View full scorecard →
VALUE
92/100
Price-to-Earnings & upside
Proven by this page
FUTURE
67/100
Analyst consensus
→ Forecast
PAST
0/100
→ Income
HEALTH
33/100
Debt-to-Equity & liquidity
→ Health
MOAT
72/100
→ Income
~
GROWTH
48/100
→ Income
INCOME
10/100
→ Income

Valuation Snapshot — IONS

Valuation Multiples
P/E (TTM)-32.1
Forward P/E65.9
PEG Ratio0.51
Forward PEG0.51
P/B Ratio25.01
P/S Ratio13.22
EV/EBITDA3.2
Per Share Data
EPS (TTM)$-2.35
Forward EPS (Est.)$1.17
Book Value / Share$3.02
Revenue / Share$5.82
FCF / Share$-1.98
Yields & Fair Value
Earnings Yield-3.11%
Forward Earnings Yield1.52%
Dividend Yield0.00%
Analyst Target$96.40 (+25.6%)

Historical Valuation

Year P/E (TTM) PEG Ratio P/B Ratio P/S Ratio Dividend Yield
2016 -95.7 35.39 58.03 15.50 -
2017 18,028.9 -193.20 22.20 12.13 -
2018 26.1 -0.01 6.83 11.93 -
2019 30.4 20.98 5.75 7.53 -
2020 -17.8 0.07 10.62 10.82 -
2021 -150.1 1.60 5.56 5.29 -
2022 -19.9 -0.02 9.35 9.12 -
2023 -19.8 -0.57 18.71 9.18 -
2024 -11.5 -0.61 8.88 7.41 -
2025 -33.2 1.53 25.88 13.41 -

EPS: Actual vs Estimates

P/E Ratio & Earnings Yield

Earnings Per Share (EPS) History

Year EPS (Diluted) Revenue Net Income Net Margin
2016 $-0.72 $346.62M $-86.56M -25%
2017 $-0.05 $507.67M $-5.97M -1.2%
2018 $2.04 $599.67M $273.74M 45.6%
2019 $2.06 $1.12B $294M 26.2%
2020 $-3.49 $729M $-487M -66.8%
2021 $-0.21 $810M $-29M -3.6%
2022 $-1.90 $587M $-270M -46%
2023 $-2.56 $787.65M $-366.29M -46.5%
2024 $-3.04 $705.14M $-453.9M -64.4%
2025 $-2.38 $944M $-381M -40.4%

Analyst Estimates

Year EPS (Avg) EPS Range Revenue (Avg) Revenue Range Analysts
2026 $-3.98 $-4.94 – $-2.14 $821.46M $739.06M – $1.08B 8
2027 $-1.15 $-6.37 – $4.55 $1.44B $1.05B – $1.6B 9
2028 $1.17 $-5.70 – $7.60 $1.98B $1.97B – $2B 10
2029 $3.29 $2.39 – $4.12 $2.76B $2.18B – $3.3B 4
2030 $6.13 $4.45 – $7.68 $3.57B $2.82B – $4.27B 4
Contact Us
🎓
SharesGrow Academy
Learn how to calculate Intrinsic Value and find undervalued stocks.
Weekly live sessions
Send us a message