There have been 50 recent insider transactions recorded for Amylyx Pharmaceuticals, Inc. (AMLX), including 17 buys and 31 sells. Total insider buying was valued at $19.97M and total insider selling at $6.08M.
Notable insiders with recent activity include Frates James M, Bedrosian Camille L, Klee Justin B.. Insider transactions can provide insights into how company leadership views the stock's valuation and future prospects.
Insider Transactions — AMLX
| Date |
Name |
Role |
Transaction |
Shares |
Avg. Price |
Value |
Shares Owned |
| 2026-03-05 |
Frates James M |
Chief Financial Officer |
RSU Award |
143,985 |
$14.10 |
$2.03M |
143,985 |
| 2026-03-05 |
Bedrosian Camille L |
Chief Medical Officer |
RSU Award |
143,985 |
$14.10 |
$2.03M |
143,985 |
| 2026-03-05 |
Klee Justin B. |
Co-chief Executive Officer |
RSU Award |
373,295 |
$14.10 |
$5.26M |
373,295 |
| 2026-03-05 |
Cohen Joshua B |
Co-chief Executive Officer |
RSU Award |
373,295 |
$14.10 |
$5.26M |
373,295 |
| 2026-03-05 |
Mazzariello Gina |
Chief Legal Officer |
RSU Award |
111,990 |
$14.10 |
$1.58M |
111,990 |
| 2026-03-02 |
Frates James M |
Chief Financial Officer |
Informative Sell |
7,909 |
$14.52 |
$114.85K |
165,638 |
| 2026-03-02 |
Bedrosian Camille L |
Chief Medical Officer |
Informative Sell |
6,461 |
$14.58 |
$94.21K |
169,295 |
| 2026-03-02 |
Klee Justin B. |
Co-chief Executive Officer |
Informative Sell |
29,282 |
$14.47 |
$423.76K |
3,334,616 |
| 2026-03-02 |
Cohen Joshua B |
Co-chief Executive Officer |
Informative Sell |
29,282 |
$14.48 |
$424.12K |
3,334,683 |
| 2026-03-02 |
Mazzariello Gina |
Chief Legal Officer |
Informative Sell |
6,844 |
$14.52 |
$99.38K |
134,430 |
| 2026-02-23 |
Mazzariello Gina |
Chief Legal Officer |
Informative Sell |
3,419 |
$14.14 |
$48.35K |
141,274 |
| 2026-02-02 |
Frates James M |
Chief Financial Officer |
Informative Sell |
3,557 |
$14.65 |
$52.1K |
173,547 |
| 2026-02-02 |
Klee Justin B. |
Co-chief Executive Officer |
Informative Sell |
15,500 |
$14.69 |
$227.62K |
3,363,898 |
| 2026-02-02 |
Cohen Joshua B |
Co-chief Executive Officer |
Informative Sell |
15,500 |
$14.68 |
$227.59K |
3,363,965 |
| 2026-02-02 |
Mazzariello Gina |
Chief Legal Officer |
Informative Sell |
3,448 |
$14.65 |
$50.52K |
144,693 |
| 2026-01-16 |
Klee Justin B. |
Co-chief Executive Officer |
Option Exercise (Sell) |
2,847 |
$7.57 |
$21.55K |
- |
| 2026-01-16 |
Cohen Joshua B |
Co-chief Executive Officer |
Option Exercise (Sell) |
2,818 |
$7.57 |
$21.33K |
- |
| 2026-01-15 |
Klee Justin B. |
Co-chief Executive Officer |
Option Exercise (Sell) |
197,153 |
$7.57 |
$1.49M |
2,847 |
| 2026-01-15 |
Cohen Joshua B |
Co-chief Executive Officer |
Option Exercise (Sell) |
197,182 |
$7.57 |
$1.49M |
2,818 |
| 2026-01-12 |
Milne George M Jr |
Director |
Gift (Given) |
17,780 |
- |
- |
812,881 |
| 2026-01-06 |
Frates James M |
Chief Financial Officer |
Informative Sell |
3,326 |
$11.11 |
$36.95K |
177,104 |
| 2026-01-06 |
Klee Justin B. |
Co-chief Executive Officer |
Informative Sell |
7,715 |
$11.09 |
$85.59K |
3,317,586 |
| 2026-01-06 |
Cohen Joshua B |
Co-chief Executive Officer |
Informative Sell |
7,715 |
$11.09 |
$85.6K |
3,317,632 |
| 2025-12-23 |
Firestone Karen |
Director |
Informative Buy |
8,100 |
$12.45 |
$100.85K |
63,100 |
| 2025-12-01 |
Bedrosian Camille L |
Chief Medical Officer |
Informative Sell |
6,580 |
$14.35 |
$94.42K |
175,756 |
| 2025-09-30 |
Frates James M |
Chief Financial Officer |
Informative Sell |
10,558 |
$14.65 |
$154.65K |
280,430 |
| 2025-09-30 |
Bedrosian Camille L |
Chief Medical Officer |
Informative Sell |
12,039 |
$14.58 |
$175.52K |
182,336 |
| 2025-09-30 |
Klee Justin B. |
Co-chief Executive Officer |
Informative Sell |
200 |
$15.01 |
$3K |
3,325,301 |
| 2025-09-30 |
Cohen Joshua B |
Co-chief Executive Officer |
Informative Sell |
200 |
$15.00 |
$3K |
3,325,347 |
| 2025-09-30 |
Mazzariello Gina |
Chief Legal Officer |
Informative Sell |
8,828 |
$14.58 |
$128.67K |
148,141 |
| 2025-08-13 |
Mazzariello Gina |
Chief Legal Officer |
Informative Sell |
15,000 |
$8.34 |
$125.05K |
156,969 |
| 2025-08-12 |
Mazzariello Gina |
Chief Legal Officer |
Informative Sell |
15,000 |
$8.07 |
$121.1K |
171,969 |
| 2025-06-05 |
Milne George M Jr |
Director |
RSU Award |
25,000 |
$5.05 |
$126.25K |
25,000 |
| 2025-06-05 |
Quimi Daphne |
Director |
RSU Award |
25,000 |
$5.05 |
$126.25K |
25,000 |
| 2025-06-05 |
Fonteyne Paul R. |
Director |
RSU Award |
25,000 |
$5.05 |
$126.25K |
25,000 |
| 2025-06-05 |
Firestone Karen |
Director |
RSU Award |
25,000 |
$5.05 |
$126.25K |
25,000 |
| 2025-06-05 |
Zeiher Bernhardt G |
Director |
RSU Award |
25,000 |
$5.05 |
$126.25K |
25,000 |
| 2025-05-22 |
Mazzariello Gina |
Chief Legal Officer |
Gift (Given) |
1,000 |
- |
- |
186,969 |
| 2025-03-31 |
Frates James M |
Chief Financial Officer |
Informative Sell |
10,896 |
$3.47 |
$37.81K |
290,988 |
| 2025-03-31 |
Bedrosian Camille L |
Chief Medical Officer |
Informative Sell |
12,425 |
$3.47 |
$43.08K |
194,375 |
| 2025-03-31 |
Klee Justin B. |
Co-chief Executive Officer |
Informative Sell |
21,490 |
$3.46 |
$74.45K |
3,355,276 |
| 2025-03-31 |
Cohen Joshua B |
Co-chief Executive Officer |
Informative Sell |
21,490 |
$3.47 |
$74.48K |
3,355,280 |
| 2025-03-31 |
Mazzariello Gina |
Chief Legal Officer |
Informative Sell |
9,192 |
$3.48 |
$31.95K |
187,969 |
| 2025-03-20 |
Zeiher Bernhardt G |
Director |
Informative Buy |
10,000 |
$3.70 |
$37.01K |
10,000 |
| 2025-03-06 |
Frates James M |
Chief Financial Officer |
RSU Award |
102,630 |
$3.61 |
$370.49K |
102,630 |
| 2025-03-06 |
Bedrosian Camille L |
Chief Medical Officer |
RSU Award |
102,630 |
$3.61 |
$370.49K |
102,630 |
| 2025-03-06 |
Klee Justin B. |
Co-chief Executive Officer |
RSU Award |
270,177 |
$3.61 |
$975.34K |
270,177 |
| 2025-03-06 |
Cohen Joshua B |
Co-chief Executive Officer |
RSU Award |
270,177 |
$3.61 |
$975.34K |
270,177 |
| 2025-03-06 |
Mazzariello Gina |
Chief Legal Officer |
RSU Award |
95,777 |
$3.61 |
$345.75K |
95,777 |
| 2025-03-03 |
Klee Justin B. |
Co-chief Executive Officer |
Informative Sell |
4,595 |
$3.15 |
$14.48K |
3,196,648 |
■ Informative Buy/Sell — open market transaction (most significant)
■ Uninformative Buy — award, option exercise, conversion
■ Uninformative Sell — tax withholding, award vest sale
■ Neutral — gift, trust, expiry
