SharesGrow 7-Criteria Score
All 7 criteria scored · valuation-related highlighted on this page
Upstream Bio, Inc. (UPB) has a negative trailing P/E of -3.7, meaning the company is currently unprofitable on a trailing twelve-month (TTM) basis. Trailing earnings yield is -27.07%.
Criteria proven by this page:
- VALUE (100/100, Pass) — analyst target implies upside (+396.5%).
- Trailing Earnings Yield -27.07% — negative yield confirms the company is currently unprofitable. Investors are paying for a turnaround rather than current earnings.
- Analyst consensus target $49.00 (+396.5% upside) — significant upside potential according to Wall Street analysts.
Overall SharesGrow Score: 52/100 with 2/7 criteria passed.
SharesGrow 7-Criteria Score
✓
VALUE
100/100
Price-to-Earnings & upside
Proven by this page
✓
HEALTH
100/100
Debt-to-Equity & liquidity
→ Health
Valuation Snapshot — UPB
Valuation Multiples
P/E (TTM)-3.7
Forward P/EN/A
PEG RatioN/A
Forward PEGN/A
P/B Ratio1.56
P/S Ratio186.27
EV/EBITDA-2.8
Per Share Data
EPS (TTM)$-2.64
Book Value / Share$6.26
Revenue / Share$0.05
FCF / Share$-2.46
Yields & Fair Value
Earnings Yield-27.07%
Dividend Yield0.00%
Analyst Target$49.00 (+396.5%)
Historical Valuation
| Year |
P/E (TTM) |
PEG Ratio |
P/B Ratio |
P/S Ratio |
Dividend Yield |
| 2022 |
-33.5 |
0.00 |
-7.53 |
659.33 |
- |
| 2023 |
-38.9 |
-0.66 |
-6.49 |
335.76 |
- |
| 2024 |
-13.4 |
-0.32 |
1.80 |
356.14 |
- |
| 2025 |
-10.2 |
-0.13 |
4.30 |
512.30 |
- |
P/E Ratio & Earnings Yield
Earnings Per Share (EPS) History
| Year |
EPS (Diluted) |
Revenue |
Net Income |
Net Margin |
| 2022 |
$-0.66 |
$1.21M |
$-23.87M |
-1969.3% |
| 2023 |
$-1.05 |
$2.38M |
$-20.54M |
-862.9% |
| 2024 |
$0.00 |
$2.37M |
$-62.81M |
-2650% |
| 2025 |
$-2.66 |
$2.85M |
$-143.44M |
-5026% |
Analyst Estimates
| Year |
EPS (Avg) |
EPS Range |
Revenue (Avg) |
Revenue Range |
Analysts |
| 2026 |
$-2.94 |
$-3.51 – $-2.61 |
$1.41M |
$1.04M – $1.77M |
7 |
| 2027 |
$-3.36 |
$-4.48 – $-2.31 |
$1.7M |
$1.45M – $1.95M |
5 |
| 2028 |
$-4.35 |
$-5.32 – $-2.84 |
$5.67M |
$4.84M – $6.5M |
5 |
| 2029 |
$-3.87 |
$-4.60 – $-3.13 |
$9.98M |
$8.51M – $11.45M |
1 |
| 2030 |
$-3.34 |
$-3.97 – $-2.70 |
$106.72M |
$91.04M – $122.41M |
1 |
