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Upstream Bio, Inc. UPB NASDAQ

NASDAQ Global Select • Healthcare • Biotechnology • US • USD

SharesGrow Score
52/100
2/7 Pass
SharesGrow Intrinsic Value
N/A
Negative cash flow
Analyst Price Target
$49.00
+396.5%

There have been 16 recent insider transactions recorded for Upstream Bio, Inc. (UPB), including 11 buys and 5 sells. Total insider buying was valued at $1.19M and total insider selling at $46.57K.

Notable insiders with recent activity include Gray Michael, Sutherland Everett Rand, Houghton Adam. Insider transactions can provide insights into how company leadership views the stock's valuation and future prospects.

Insider Transactions — UPB

Date Name Role Transaction Shares Avg. Price Value Shares Owned
2026-03-16 Gray Michael CFO and COO Informative Sell 852 $9.29 $7.92K 29,648
2026-03-16 Sutherland Everett Rand Chief Executive Officer Informative Sell 2,093 $9.29 $19.44K 72,907
2026-03-16 Houghton Adam Chief Business Officer Informative Sell 699 $9.29 $6.49K 24,301
2026-03-16 Deykin Aaron Chief Medical Officer Informative Sell 894 $9.29 $8.31K 32,687
2026-03-16 Ambrose Allison General Counsel Informative Sell 475 $9.29 $4.41K 16,525
2026-01-02 Gray Michael CFO and COO RSU Award 30,500 - - 30,500
2026-01-02 Sutherland Everett Rand Chief Executive Officer RSU Award 75,000 - - 75,000
2026-01-02 Houghton Adam Chief Business Officer RSU Award 25,000 - - 25,000
2026-01-02 Deykin Aaron Chief Medical Officer RSU Award 32,000 - - 33,581
2026-01-02 Ambrose Allison General Counsel RSU Award 17,000 - - 17,000
2025-06-10 Renaud Ronald C Jr Director RSU Award 17,096 $11.59 $198.14K 17,096
2025-06-10 Beckman Daniella Director RSU Award 17,096 $11.59 $198.14K 17,096
2025-06-10 Ratcliffe Liam Director RSU Award 17,096 $11.59 $198.14K 17,096
2025-06-10 Chimovits Erez Director RSU Award 17,096 $11.59 $198.14K 17,096
2025-06-10 Fleming Harold Edward Director RSU Award 17,096 $11.59 $198.14K 17,096
2025-06-10 Ruddy Marcella K. Director RSU Award 17,096 $11.59 $198.14K 17,096
Informative Buy/Sell — open market transaction (most significant) Uninformative Buy — award, option exercise, conversion Uninformative Sell — tax withholding, award vest sale Neutral — gift, trust, expiry
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